Molecular structure of AZD6482, CAS Number: 1173900-33-8
AZD6482 (CAS 1173900-33-8)
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Alternate Names:
(R)-2-(1-(7-methyl-2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethylamino)benzoic acid
Application:
AZD6482 is a PI3K inhibitor and antiplatelet agent
CAS Number:
1173900-33-8
Purity:
≥98%
Molecular Weight:
408.45
Molecular Formula:
C22H24N4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
AZD6482 inhibits PI3Kα, β, γ, and δ, with IC50 of 21 nM to 1.4 μM. AZD6482 is an antiplatelet agent; it blocks platelet activation adhesion/aggregation and promotes platelet disaggregation in an assay of washed platelet aggregation (WPA), with an IC50 value of 6 nM. Furthermore, by targeting PI3Kβ, AZD6482 specifically inhibits thrombosis without interfering with normal haemostasis.
Inhibitor of:
βPAK, BMPR-IA, KRTAP25-1, PI 3-kinase p101, PI 3-kinase p110, Plk, SMC1β, and TAPP1.Activator of:
PI 3-kinase p55γ.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AZD6482, 5 mg | sc-364422 | 5 mg | $275.00 | |||
AZD6482, 10 mg | sc-364422A | 10 mg | $390.00 |