Molecular structure of Azaspiracid-3, CAS Number: 265996-93-8
Azaspiracid-3 (CAS 265996-93-8)
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Application:
Azaspiracid-3 is a modulator of intracellular cAMP, calcium and pH levels
CAS Number:
265996-93-8
Molecular Weight:
827.5
Molecular Formula:
C46H69NO12
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Azaspiracid-3 is a modulator of intracellular cAMP (cyclic adenosine monophosphate), calcium and pH levels.
Azaspiracid-3 (CAS 265996-93-8) References
- Effects of Azaspiracids 2 and 3 on intracellular cAMP, [Ca2+], and pH. | Román, Y., et al. 2004. Chem Res Toxicol. 17: 1338-49. PMID: 15487894
- Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3. | Nicolaou, KC., et al. 2006. Angew Chem Int Ed Engl. 45: 2609-15. PMID: 16548033
- Azaspiracids modulate intracellular pH levels in human lymphocytes. | Alfonso, A., et al. 2006. Biochem Biophys Res Commun. 346: 1091-9. PMID: 16793022
- Freeze-drying for the stabilisation of shellfish toxins in mussel tissue (Mytilus edulis) reference materials. | McCarron, P., et al. 2007. Anal Bioanal Chem. 387: 2475-86. PMID: 17256111
- The preparation of certified calibration solutions for azaspiracid-1, -2, and -3, potent marine biotoxins found in shellfish. | Perez, RA., et al. 2010. Anal Bioanal Chem. 398: 2243-52. PMID: 20827466
- Effect of uncontrolled factors in a validated liquid chromatography-tandem mass spectrometry method question its use as a reference method for marine toxins: major causes for concern. | Otero, P., et al. 2011. Anal Chem. 83: 5903-11. PMID: 21651235
- Investigation of the genotoxic potential of the marine biotoxins azaspiracid 1-3. | Doerr, B., et al. 2016. Toxicon. 121: 61-69. PMID: 27576062
- Toxic equivalency factors (TEFs) after acute oral exposure of azaspiracid 1, -2 and -3 in mice. | Pelin, M., et al. 2018. Toxicol Lett. 282: 136-146. PMID: 29107028
- Stereochemical Definition of the Natural Product (6R,10R,13R, 14R,16R,17R,19S,20S,21R,24S,25S,28S,30S,32R,33R,34R,36S,37S,39R)-Azaspiracid-3 by Total Synthesis and Comparative Analyses. | Kenton, NT., et al. 2018. Angew Chem Int Ed Engl. 57: 810-813. PMID: 29193497
- Total Synthesis of (6R,10R,13R,14R,16R,17R,19S,20R,21R,24S, 25S,28S,30S,32R,33R,34R,36S,37S,39R)-Azaspiracid-3 Reveals Non-Identity with the Natural Product. | Kenton, NT., et al. 2018. Angew Chem Int Ed Engl. 57: 805-809. PMID: 29193614
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Azaspiracid-3, 0.5 µg | sc-202484 | 0.5 µg | $400.00 |