Molecular structure of Azaspiracid-2, CAS Number: 265996-92-7
Azaspiracid-2 (CAS 265996-92-7)
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Application:
Azaspiracid-2 is a modulator of intracellular cAMP & calcium levels
CAS Number:
265996-92-7
Molecular Weight:
856.1
Molecular Formula:
C48H73NO12
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Azaspiracid-2 is a modulator of intracellular cAMP (cyclic adenosine monophosphate) and calcium levels.
Azaspiracid-2 (CAS 265996-92-7) References
- Effects of Azaspiracids 2 and 3 on intracellular cAMP, [Ca2+], and pH. | Román, Y., et al. 2004. Chem Res Toxicol. 17: 1338-49. PMID: 15487894
- Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3. | Nicolaou, KC., et al. 2006. Angew Chem Int Ed Engl. 45: 2609-15. PMID: 16548033
- Azaspiracids modulate intracellular pH levels in human lymphocytes. | Alfonso, A., et al. 2006. Biochem Biophys Res Commun. 346: 1091-9. PMID: 16793022
- Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl ester in cultured neurons: involvement of the c-Jun N-terminal kinase. | Vale, C., et al. 2008. J Neurosci Res. 86: 2952-62. PMID: 18500761
- Azaspiracid substituent at C1 is relevant to in vitro toxicity. | Vilariño, N., et al. 2008. Chem Res Toxicol. 21: 1823-31. PMID: 18707138
- Isolation of azaspiracid-2 from a marine sponge Echinoclathria sp. as a potent cytotoxin. | Ueoka, R., et al. 2009. Toxicon. 53: 680-4. PMID: 19233223
- In vivo arrhythmogenicity of the marine biotoxin azaspiracid-2 in rats. | Ferreiro, SF., et al. 2014. Arch Toxicol. 88: 425-34. PMID: 23934164
- In vitro chronic effects on hERG channel caused by the marine biotoxin azaspiracid-2. | Ferreiro, SF., et al. 2014. Toxicon. 91: 69-75. PMID: 25286396
- Azadinium poporum from the Argentine Continental Shelf, Southwestern Atlantic, produces azaspiracid-2 and azaspiracid-2 phosphate. | Tillmann, U., et al. 2016. Harmful Algae. 51: 40-55. PMID: 28003061
- Azaspiracid accumulation in Japanese coastal bivalves and ascidians fed with Azadinium poporum producing azaspiracid-2 as the dominant toxin component. | Ozawa, M., et al. 2023. Toxicon. 226: 107069. PMID: 36871920
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Azaspiracid-2, 0.5 µg | sc-202483 | 0.5 µg | $359.00 |