Molecular structure of Avenanthramide-C methyl ester, CAS Number: 955382-52-2
Avenanthramide-C methyl ester (CAS 955382-52-2)
Alternate Names:
2-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]5-hydroxy-benzoic acid, methyl ester
Application:
Avenanthramide-C methyl ester is an inhibitor NF-κB activation
CAS Number:
955382-52-2
Purity:
≥95%
Molecular Weight:
329.31
Molecular Formula:
C17H15NO6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Avenanthramide-C methyl ester inhibits NF-κB activation by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM) (1). Through this mechanism, avenanthramide-C methyl ester dose dependently inhibits the secretion and expression of IL-6, IL-8, and MCP-1 in human aortic endothelial cells (1).
Avenanthramide-C methyl ester (CAS 955382-52-2) References
1 Guo, W., Wise, M.L., Collins, F.W., et al. Avenanthramides, polyphenols from oats, inhibit IL-1β-induced NF-κB activation in endothelial cells. Free Radic Biol Med 44 415-429 (2008).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Avenanthramide-C methyl ester, 500 µg | sc-223786 | 500 µg | $108.00 | |||
Avenanthramide-C methyl ester, 1 mg | sc-223786A | 1 mg | $160.00 |