Date published: 2026-4-25

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Avarone (CAS 55303-99-6)

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Application:
Avarone is a cystostatic agent which displays antibacterial and antifungal activities
CAS Number:
55303-99-6
Molecular Weight:
312.5
Molecular Formula:
C21H28O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Avarone is a quinone derivative with notable applications in biochemical and environmental research due to its redox properties. This compound acts by undergoing reversible reduction and oxidation reactions, which makes it an essential tool in studies focused on redox biology, oxidative stress, and the redox regulation of cellular processes. Avarone′s mechanism involves the acceptance and donation of electrons in chemical reactions, a feature exploited in research to investigate the molecular basis of oxidative damage and antioxidant defense mechanisms within cells. It is particularly useful in studies assessing the impact of oxidative stress on cell viability, DNA, proteins, and lipids. Moreover, avarone is employed in environmental science to explore the degradation of pollutants through redox reactions, contributing to a broader understanding of chemical reactions in natural and polluted environments. Its role in generating reactive oxygen species under specific conditions also provides insights into the environmental fate of similar quinonic compounds and their interactions with biological systems. Avarone′s ability to influence redox-sensitive pathways makes it a vital chemical in fundamental research exploring the complex balance of redox processes in biological and environmental systems.


Avarone (CAS 55303-99-6) References

  1. Effect of avarol and avarone on in vitro-induced microsomal lipid peroxidation.  |  Belisario, MA., et al. 1992. Toxicology. 72: 221-33. PMID: 1566281
  2. Evaluation of the activity of the sponge metabolites avarol and avarone and their synthetic derivatives against fouling micro- and macroorganisms.  |  Tsoukatou, M., et al. 2007. Molecules. 12: 1022-34. PMID: 17873837
  3. Effect of avarol, avarone and nine of their natural and synthetic derivatives on microsomal drug-metabolizing enzymes.  |  Belisario, MA., et al. 1991. Toxicol Lett. 57: 183-93. PMID: 1853363
  4. Cytotoxic terpene quinones from marine sponges.  |  Gordaliza, M. 2010. Mar Drugs. 8: 2849-70. PMID: 21339953
  5. Studies on the interactions of bioactive quinone avarone and its methylamino derivatives with calf thymus DNA.  |  Vujčić, MT., et al. 2013. Int J Biol Macromol. 62: 405-10. PMID: 24080453
  6. Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models.  |  Kolarević, S., et al. 2019. Drug Chem Toxicol. 42: 130-139. PMID: 29299944
  7. Evidence of Insulin-Sensitizing and Mimetic Activity of the Sesquiterpene Quinone Avarone, a Protein Tyrosine Phosphatase 1B and Aldose Reductase Dual Targeting Agent from the Marine Sponge Dysidea avara.  |  Casertano, M., et al. 2023. Pharmaceutics. 15: PMID: 36839851
  8. Antibacterial and antifungal activity of Avarone and Avarol.  |  Seibert, G., et al. 1985. Zentralbl Bakteriol Mikrobiol Hyg A. 260: 379-86. PMID: 3841441
  9. Avarol and avarone, two new anti-inflammatory agents of marine origin.  |  Ferrándiz, ML., et al. 1994. Eur J Pharmacol. 253: 75-82. PMID: 8013550
  10. In vitro effect of avarone and avarol, a quinone/hydroquinone couple of marine origin, on platelet aggregation.  |  Belisario, MA., et al. 1996. Pharmacol Toxicol. 79: 300-4. PMID: 9000256

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Avarone, 1 mg

sc-202481
1 mg
$130.00