Autocamtide-2 Peptide
Alternate Names:
KKALRRQETVDAL; Calcium/calmodulin-dependent protein kinase type II alpha chain; KIAA0968
Application:
Autocamtide-2 Peptide is a highly selective peptide substrate for CaM Kinase II
Purity:
≥95%
Molecular Weight:
1527.8
Molecular Formula:
C65H118N22O20
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
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SDS & Certificate of Analysis
CaM Kinase II Substrate is a synthetic substrate for CaM Kinase II. Corresponds to sequence derived from CaM Kinase II autophosphorylation site.
Autocamtide-2 Peptide References
- Long-lasting decrease in neuronal Ca2+/calmodulin-dependent protein kinase II activity in a hippocampal neuronal culture model of spontaneous recurrent seizures. | Blair, RE., et al. 1999. Brain Res. 851: 54-65. PMID: 10642828
- Light scattering and transmission electron microscopy studies reveal a mechanism for calcium/calmodulin-dependent protein kinase II self-association. | Hudmon, A., et al. 2001. J Neurochem. 76: 1364-75. PMID: 11238721
- Calmodulin and calmodulin-dependent kinase II mediate neuronal cell death induced by depolarization. | Takano, H., et al. 2003. Brain Res. 962: 41-7. PMID: 12543454
- Differential expression of CaMK-II genes during early zebrafish embryogenesis. | Rothschild, SC., et al. 2007. Dev Dyn. 236: 295-305. PMID: 17103413
- Cadmium activates CaMK-II and initiates CaMK-II-dependent apoptosis in mesangial cells. | Liu, Y. and Templeton, DM. 2007. FEBS Lett. 581: 1481-6. PMID: 17367784
- Calcium/calmodulin-dependent kinase II plays an important role in prostate cancer cell survival. | Rokhlin, OW., et al. 2007. Cancer Biol Ther. 6: 732-42. PMID: 17387273
- Induction of immediate early genes by Ca2+ influx requires cAMP-dependent protein kinase in PC12 cells. | Ginty, DD., et al. 1991. J Biol Chem. 266: 17454-8. PMID: 1910045
- Cardioprotective 3',4'-dihydroxyflavonol attenuation of JNK and p38(MAPK) signalling involves CaMKII inhibition. | Lim, NR., et al. 2013. Biochem J. 456: 149-61. PMID: 24032640
- Structural analysis of a calmodulin variant from rice: the C-terminal extension of OsCaM61 regulates its calcium binding and enzyme activation properties. | Jamshidiha, M., et al. 2013. J Biol Chem. 288: 32036-49. PMID: 24052265
- The CaMKII phosphorylation site Thr1604 in the CaV1.2 channel is involved in pathological myocardial hypertrophy in rats. | Li, J., et al. 2020. Channels (Austin). 14: 151-162. PMID: 32290730
- Translocation of autophosphorylated calcium/calmodulin-dependent protein kinase II to the postsynaptic density. | Strack, S., et al. 1997. J Biol Chem. 272: 13467-70. PMID: 9153188
- Heparin inhibits Ca2+/calmodulin-dependent kinase II activation and c-fos induction in mesangial cells. | Miralem, T. and Templeton, DM. 1998. Biochem J. 330 (Pt 2): 651-7. PMID: 9480871
- Ca(2+)-induced loss of Ca2+/calmodulin-dependent protein kinase II activity in pancreatic beta-cells. | Jones, PM. and Persaud, SJ. 1998. Am J Physiol. 274: E708-15. PMID: 9575833
Substrate of:
CaMKII.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Autocamtide-2 Peptide, 1 mg | sc-3029 | 1 mg | $95.00 |