Molecular structure of Aurintricarboxylic acid ammonium salt, CAS Number: 569-58-4
Aurintricarboxylic acid ammonium salt (CAS 569-58-4)
Alternate Names:
Aluminon
Application:
Aurintricarboxylic acid ammonium salt is a free radical generating inhibitor of ribonuclease and topoisomerase II
CAS Number:
569-58-4
Molecular Weight:
473.43
Molecular Formula:
C22H14O9•3NH3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Aluminum reagent that readily polymerizes in solution (aq), producing a free radical that inhibits protein-nucleic acid interactions. Inhibits ribonuclease and topoisomerase Il2 through the prevention of enzyme-nucleic acid binding. Stimulates tyrosine phosphorylation and inhibits apoptosis in many cell types.
Aurintricarboxylic acid ammonium salt (CAS 569-58-4) References
- Aurintricarboxylic acid and its metal ion complexes in comparative virtual screening versus Lopinavir and Hydroxychloroquine in fighting COVID-19 pandemic: Synthesis and characterization. | Refat, MS., et al. 2021. Inorg Chem Commun. 126: 108472. PMID: 33531865
- Application of CRISPR/Cas9 Tools for Genome Editing in the White-Rot Fungus Dichomitus squalens. | Kowalczyk, JE., et al. 2021. Biomolecules. 11: PMID: 34680159
- Aurintricarboxylic Acid Decreases RNA Toxicity in a C. elegans Model of Repeat Expansions. | Braun, M., et al. 2021. Toxins (Basel). 13: PMID: 34941747
- Mechanism of action of polymeric aurintricarboxylic acid, a potent inhibitor of protein--nucleic acid interactions. | González, RG., et al. 1980. Biochemistry. 19: 4299-303. PMID: 6158332
- A neuroprotective compound, aurin tricarboxylic acid, stimulates the tyrosine phosphorylation cascade in PC12 cells. | Okada, N. and Koizumi, S. 1995. J Biol Chem. 270: 16464-9. PMID: 7608219
- Aurintricarboxylic acid is an inhibitor of mu- and m-calpain. | Posner, A., et al. 1995. Biochem Mol Biol Int. 36: 291-9. PMID: 7663433
- Aurintricarboxylic acid, a putative inhibitor of apoptosis, is a potent inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells. | Benchokroun, Y., et al. 1995. Biochem Pharmacol. 49: 305-13. PMID: 7857317
- Tyrosine phosphorylation of ErbB4 is stimulated by aurintricarboxylic acid in human neuroblastoma SH-SY5Y cells. | Okada, N. and Koizumi, S. 1997. Biochem Biophys Res Commun. 230: 266-9. PMID: 9016763
- Activation of the Jak2-Stat5 signaling pathway in Nb2 lymphoma cells by an anti-apoptotic agent, aurintricarboxylic acid. | Rui, H., et al. 1998. J Biol Chem. 273: 28-32. PMID: 9417042
- Aurintricarboxylic acid prevents GLUR2 mRNA down-regulation and delayed neurodegeneration in hippocampal CA1 neurons of gerbil after global ischemia. | Aronica, EM., et al. 1998. Proc Natl Acad Sci U S A. 95: 7115-20. PMID: 9618548
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aurintricarboxylic acid ammonium salt, 25 g | sc-210849 | 25 g | $44.00 | |||
Aurintricarboxylic acid ammonium salt, 100 g | sc-210849A | 100 g | $124.00 |