Aureusimine B CAS: 170713-71-0
MF: C14H16N2O
MW: 228.29
A small molecular weight monoketopiperazine.

Aureusimine B (CAS 170713-71-0)

Aureusimine B | CAS 170713-71-0 is rated 5.0 out of 5 by 1.
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Alternate Names: Phevalin; 3-(1-Methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone
Application: Aureusimine B is a small molecular weight monoketopiperazine
CAS Number: 170713-71-0
Molecular Weight: 228.29
Molecular Formula: C14H16N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Aureusimine B (phevalin) is a small molecular weight monoketopiperazine formed non-ribosomally by the fusion of phenylalanine and valine. Aureusimine B was isolated from S. aureus in 2010 as one of a pair of related metabolites controversially identified as virulence factors in the pathology of Golden Staph. Aureusimine B has also been reported as an inhibitor of the protease, calpain.

Physical State :
Solid
Derived From :
Synthetic
Solubility :
Soluble in ethanol, methanol, DMSO, DMF, and water (poor).
Storage :
Store at -20° C
Melting Point :
164.58° C (Predicted)
Boiling Point :
405.14° C (Predicted)
Density :
~1.1 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
10376483
SMILES :
CC(C)C1=NC=C(NC1=O)CC2=CC=CC=C2

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Certificate of Analysis

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Aureusimine B (CAS 170713-71-0)  Product Citations

See how others have used Aureusimine B (CAS 170713-71-0). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 27632173  PLoS Pathog. 12: e1005857.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Secor et al Secor et al. (PubMed ID 22808288) found that Aureusimine B (Phevalin) produced by Staphylococcus aureus biofilm could be a potential therapeutic target. -SCBT Publication Review
Date published: 2015-01-06
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