Aureothin CAS: 2825-00-5
MF: C22H23NO6
MW: 397.42
An antifungal and antibacterial agent that inhibits of oxidoreductase.

Aureothin (CAS 2825-00-5)

Aureothin | CAS 2825-00-5 is rated 5.0 out of 5 by 1.
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Synonym: Mycolutein, Distacin; Strain 58 substance
Application: An antifungal and antibacterial agent that inhibits of oxidoreductase
CAS Number: 2825-00-5
Purity: ≥96%
Molecular Weight: 397.42
Molecular Formula: C22H23NO6
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Aureothin is an inhibitor of TrxR1 (oxidoreductase). Has broad biological actions including antitrypanosomal, antibacterial (against Helicobacter pylori), antitumor, antifungal, insecticidal, pesticidal activities.


References

1. Washizu, F., et al. 1954. J. Antibiot. 7: 60. PMID: 13174453
2. Schwartz, J.L., et al. 1976. J. Antibiot. 29: 236-241. PMID: 770405
3. Friedrich, T., et al. 1994. Eur. J. Biochem. 219: 691-698. PMID: 8307034
4. Taniguchi, M., et al. 2000. J. Antibiot. 53: 844-847. PMID: 11079808
5. Ueda, J.Y., et al. 2007. J. Antibiot. 60: 321-324. PMID: 17551211
6. Otoguro, K., et al. 2008. J. Antibiot. 61: 372-378. PMID: 18667785
7. Werneburg, M. and Hertweck,C. 2008. Chembiochem. 9: 2064-2066. PMID: 1869065
8. Otoguro, K., et al. 2008. J. Antibiot. 61: 372-378. PMID: 18667785

Physical State :
Solid
Derived From :
Streptomyces thioluteus
Solubility :
Soluble in 100% ethanol, methanol, DMSO, DMF, dichloromethane, and acetone.
Storage :
Store at -20° C
Melting Point :
219.95° C (Predicted)
Boiling Point :
585.93° C at 760 mmHg (Predicted)
Density :
1.27 g/cm3 (Predicted)
Refractive Index :
n20D 1.59 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
UQ0800000
PubChem CID :
6436188
Merck Index :
10: 879
Beilstein Registry :
58476
SMILES :
CC1=C(OC(=C(C1=O)C)OC)[[email protected]]2CC/C(=C/C(=C/C3=CC=C(C=C3)[N+](=O)[O-])/C)/O2

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Otoguro et al Otoguro et al. (PubMed ID18667785) found that aureothin is a selective and potent inhibitor of antitrypanosomal activity in vitro. -SCBT Publication Review
Date published: 2015-01-24
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