Molecular structure of Aucubin, CAS Number: 479-98-1
Aucubin (CAS 479-98-1)
Application:
Aucubin is an analytical standard that exhibits antioxidant and protective effects in mice
CAS Number:
479-98-1
Purity:
≥98%
Molecular Weight:
346.33
Molecular Formula:
C15H22O9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Aucubine is an analytical standard with many uses in biochemical research. For example, it exhibits antioxidant and protective effects for the liver and kidney organs, shown in mice with induced diabetes. Aucubin, a naturally occurring triterpenoid saponin, is abundantly present in various plants, such as the European Aucuba japonica. It constitutes a significant portion of the plant′s saponin fraction and exhibits diverse biological activities, including anti-inflammatory, antioxidant, and anti-cancer properties.
Aucubin (CAS 479-98-1) References
- Aucubin Alleviates Bleomycin-Induced Pulmonary Fibrosis in a Mouse Model. | Zhou, Y., et al. 2017. Inflammation. 40: 2062-2073. PMID: 28785877
- Aucubin protects against pressure overload-induced cardiac remodelling via the β3 -adrenoceptor-neuronal NOS cascades. | Wu, QQ., et al. 2018. Br J Pharmacol. 175: 1548-1566. PMID: 29447430
- Aucubin inhibited lipid accumulation and oxidative stress via Nrf2/HO-1 and AMPK signalling pathways. | Shen, B., et al. 2019. J Cell Mol Med. 23: 4063-4075. PMID: 30950217
- Aucubin Protects Chondrocytes Against IL-1β-Induced Apoptosis In Vitro And Inhibits Osteoarthritis In Mice Model. | Wang, BW., et al. 2019. Drug Des Devel Ther. 13: 3529-3538. PMID: 31631977
- A review of the pharmacology and toxicology of aucubin. | Zeng, X., et al. 2020. Fitoterapia. 140: 104443. PMID: 31790767
- Aucubin, An Active Ingredient in Aucuba japonica, Prevents N-methyl-N-nitrosourea-induced Retinal Degeneration in Mice. | Jung, E., et al. 2019. Molecules. 24: PMID: 31817154
- Aucubin administered by either oral or parenteral route protects against cisplatin-induced acute kidney injury in mice. | Potočnjak, I., et al. 2020. Food Chem Toxicol. 142: 111472. PMID: 32504734
- Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury. | Wang, H., et al. 2020. J Neuroinflammation. 17: 188. PMID: 32539839
- Aucubin prevents steroid-induced osteoblast apoptosis by enhancing autophagy via AMPK activation. | Yue, C., et al. 2021. J Cell Mol Med. 25: 10175-10184. PMID: 34612603
- Research progress on the protective effects of aucubin in neurological diseases. | Yang, P., et al. 2022. Pharm Biol. 60: 1088-1094. PMID: 35634723
- Aucubin ameliorates liver fibrosis and hepatic stellate cells activation in diabetic mice via inhibiting ER stress-mediated IRE1α/TXNIP/NLRP3 inflammasome through NOX4/ROS pathway. | Bao, X., et al. 2022. Chem Biol Interact. 365: 110074. PMID: 35961541
- Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model. | Xiao, S., et al. 2022. Int Immunopharmacol. 111: 109163. PMID: 35994851
- Aucubin administration suppresses STING signaling and mitigated high-fat diet-induced atherosclerosis and steatohepatosis in LDL receptor deficient mice. | Liu, Y., et al. 2022. Food Chem Toxicol. 169: 113422. PMID: 36108984
- Aucubin Impeded Preosteoclast Fusion and Enhanced CD31hi EMCNhi Vessel Angiogenesis in Ovariectomized Mice. | Li, Z., et al. 2022. Stem Cells Int. 2022: 5226771. PMID: 36406003
- Characteristics, Isolation Methods, and Biological Properties of Aucubin. | Kartini, K., et al. 2023. Molecules. 28: PMID: 37241895
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aucubin, 5 mg | sc-233897 | 5 mg | $72.00 |