Atropine-d5 (CAS 5908-99-6 unlabeled)
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Alternate Names:
α-(Hydroxymethyl)benzeneacetic Acid-d5 (3-endo)-8-Methyl-8-azabicyclo[3.2.1] oct-3-yl Ester; Atropisol-d5; Atropt-d5
Application:
Atropine-d5 is a mydriatic and antispasmodic labeled form of Atropine
CAS Number:
5908-99-6 unlabeled
Molecular Weight:
294.40
Molecular Formula:
C17H18D5NO3
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Atropine-d5 is the labeled form of Atropine (sc-252392). Deuterated compounds like Atropine-d5 are invaluable as internal standards in mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy, providing more accurate and precise measurements due to their similar chemical behavior but different physical properties compared to their non-deuterated counterparts. Atropine-d5 can be used to track the absorption, distribution, metabolism, and excretion (ADME) of atropine in biological systems with higher resolution.
Atropine-d5 (CAS 5908-99-6 unlabeled) References
- Impact of Chemical Structure on Conjunctival Drug Permeability: Adopting Porcine Conjunctiva and Cassette Dosing for Construction of In Silico Model. | Ramsay, E., et al. 2017. J Pharm Sci. 106: 2463-2471. PMID: 28479360
- Melanin binding study of clinical drugs with cassette dosing and rapid equilibrium dialysis inserts. | Pelkonen, L., et al. 2017. Eur J Pharm Sci. 109: 162-168. PMID: 28756205
- Validation of a fully automated solid-phase extraction and ultra-high-performance liquid chromatography-tandem mass spectrometry method for quantification of 30 pharmaceuticals and metabolites in post-mortem blood and brain samples. | Nielsen, MKK., et al. 2018. Drug Test Anal.. PMID: 29341495
- Binding of Small Molecule Drugs to Porcine Vitreous Humor. | Rimpelä, AK., et al. 2018. Mol Pharm. 15: 2174-2179. PMID: 29648838
- Simultaneous determination of 16 alkaloids in blood by ultrahigh-performance liquid chromatography-tandem mass spectrometry coupled with supported liquid extraction. | Chen, R., et al. 2019. J Chromatogr B Analyt Technol Biomed Life Sci. 1128: 121789. PMID: 31525720
- Obtaining clean and informative mass spectra from complex chromatographic and high-resolution all-ions-fragmentation data by nonnegative parallel factor analysis 2. | Kronik, OM., et al. 2022. J Chromatogr A. 1682: 463501. PMID: 36155072
- Development of a Novel LC-MS/MS Multi-Method for the Determination of Regulated and Emerging Food Contaminants Including Tenuazonic Acid, a Chromatographically Challenging Alternaria Toxin. | Tölgyesi, Á., et al. 2023. Molecules. 28: PMID: 36771134
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Atropine-d5, 2.5 mg | sc-217678 | 2.5 mg | $337.00 |