Atrazine Mercapturate (CAS 138722-96-0)
QUICK LINKS
Atrazine mercapturate serves as a chemical compound extensively utilized in diverse scientific research applications. Derived from atrazine, a widely employed herbicide and pesticide, it has proven valuable in various scientific fields, including biochemistry and physiology. Throughout scientific research, Atrazine mercapturate has found multiple applications. Notably, it has been employed to investigate the environmental and human health effects of atrazine. Moreover, studies have utilized it to explore enzyme inhibition, especially in relation to atrazine metabolism. Additionally, the compound has been instrumental in examining the influence of atrazine on the growth of bacteria and fungi. The mechanism of action of Atrazine mercapturate involves its role as an inhibitor of the enzyme acetylcholinesterase, a regulator of neurotransmission in the nervous system. By binding to the enzyme′s active site, it impedes the breakdown of acetylcholine, leading to increased concentrations of acetylcholine in the nervous system. This elevated concentration yields diverse physiological effects.
Atrazine Mercapturate (CAS 138722-96-0) References
- A longitudinal investigation of selected pesticide metabolites in urine. | MacIntosh, DL., et al. 1999. J Expo Anal Environ Epidemiol. 9: 494-501. PMID: 10554151
- Urinary biomarkers of atrazine exposure among farm pesticide applicators. | Perry, M., et al. 2000. Ann Epidemiol. 10: 479. PMID: 11018424
- Collecting urine samples from young children using cotton gauze for pesticide studies. | Hu, YA., et al. 2000. J Expo Anal Environ Epidemiol. 10: 703-9. PMID: 11138662
- Biological monitoring for selected herbicide biomarkers in the urine of exposed custom applicators: application of mixed-effect models. | Hines, CJ., et al. 2003. Ann Occup Hyg. 47: 503-17. PMID: 12890659
- Quantification of atrazine, phenylurea, and sulfonylurea herbicide metabolites in urine by high-performance liquid chromatography-tandem mass spectrometry. | Nguyen, JV., et al. 2007. J Anal Toxicol. 31: 181-6. PMID: 17555640
- Improved methods for urinary atrazine mercapturate analysis--assessment of an enzyme-linked immunosorbent assay (ELISA) and a novel liquid chromatography-mass spectrometry (LC-MS) method utilizing online solid phase extraction (SPE). | Koivunen, ME., et al. 2006. Anal Chim Acta. 572: 180-9. PMID: 17723476
- Exposure to atrazine and selected non-persistent pesticides among corn farmers during a growing season. | Bakke, B., et al. 2009. J Expo Sci Environ Epidemiol. 19: 544-54. PMID: 19052531
- Quantum Dots as Reporters in Multiplexed Immunoassays for Biomarkers of Exposure to Agrochemicals. | Nichkova, M., et al. 2007. Anal Lett. 40: 1423-1433. PMID: 19079795
- Agrichemicals in surface water and birth defects in the United States. | Winchester, PD., et al. 2009. Acta Paediatr. 98: 664-9. PMID: 19183116
- Comparison of immunoassay and HPLC-MS/MS used to measure urinary metabolites of atrazine, metolachlor, and chlorpyrifos from farmers and non-farmers in Iowa. | Curwin, BD., et al. 2010. J Expo Sci Environ Epidemiol. 20: 205-12. PMID: 19277069
- Urinary biomarkers of prenatal atrazine exposure and adverse birth outcomes in the PELAGIE birth cohort. | Chevrier, C., et al. 2011. Environ Health Perspect. 119: 1034-41. PMID: 21367690
- Urinary metabolites as biomarkers of human exposure to atrazine: atrazine mercapturate in agricultural workers. | Mendaš, G., et al. 2012. Toxicol Lett. 210: 174-81. PMID: 22155356
- A longitudinal study of atrazine and 2,4-D exposure and oxidative stress markers among iowa corn farmers. | Lerro, CC., et al. 2017. Environ Mol Mutagen. 58: 30-38. PMID: 28116766
- Mechanisms of Neurotoxicity Associated with Exposure to the Herbicide Atrazine. | Stradtman, SC. and Freeman, JL. 2021. Toxics. 9: PMID: 34564358
- Influence of GSTM1, T1 genes polymorphisms on oxidative stress and liver enzymes in rural and urban pesticides-exposed workers. | Saad-Hussein, A., et al. 2022. Arch Environ Occup Health. 77: 800-808. PMID: 35014941
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Atrazine Mercapturate, 5 mg | sc-210847 | 5 mg | $367.00 |