Date published: 2025-9-5

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Atenolol-d7 (CAS 1202864-50-3)

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Application:
Atenolol-d7 is a cardioselective β-adrenergic blocker
CAS Number:
1202864-50-3
Purity:
Isotopic purity: 98%
Molecular Weight:
273.38
Molecular Formula:
C14H15D7N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Atenolol-d7 is a deuterated form of atenolol, often used as an internal standard for analytical purposes in various research studies. The incorporation of seven deuterium atoms allows for differentiation from atenolol itself during mass spectrometry, enhancing the accuracy of quantitative analyses. This compound is especially significant in the field of metabolomics, where it helps in tracing the metabolic fate of atenolol through biological systems. Researchers also use atenolol-d7 to study the environmental impact of beta-blockers, as it can act as a stable tracer that withstands degradation processes better than its non-deuterated counterpart. Additionally, its presence in reaction mixtures aids in the investigation of kinetic isotope effects, providing insights into reaction mechanisms and the influence of atomic mass on chemical processes.


Atenolol-d7 (CAS 1202864-50-3) References

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  3. Simultaneous quantification of atenolol and chlorthalidone in human plasma by ultra-performance liquid chromatography-tandem mass spectrometry.  |  Shah, JV., et al. 2016. Biomed Chromatogr. 30: 208-16. PMID: 26096961
  4. Rapid chiral separation of atenolol, metoprolol, propranolol and the zwitterionic metoprolol acid using supercritical fluid chromatography-tandem mass spectrometry - Application to wetland microcosms.  |  Svan, A., et al. 2015. J Chromatogr A. 1409: 251-8. PMID: 26228849
  5. Potential impact of the sewer system on the applicability of alcohol and tobacco biomarkers in wastewater-based epidemiology.  |  Banks, APW., et al. 2018. Drug Test Anal. 10: 530-538. PMID: 28688172
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  7. Using Sesame Seed Oil to Preserve and Preconcentrate Cannabinoids for Paper Spray Mass Spectrometry.  |  Bills, B. and Manicke, N. 2020. J Am Soc Mass Spectrom. 31: 675-684. PMID: 32013413
  8. Topical ocular pharmacokinetics and bioavailability for a cocktail of atenolol, timolol and betaxolol in rabbits.  |  Fayyaz, A., et al. 2020. Eur J Pharm Sci. 155: 105553. PMID: 32946960
  9. Application of multi-parameter population model based on endogenous population biomarkers and flow volume in wastewater epidemiology.  |  Hou, C., et al. 2021. Sci Total Environ. 759: 143480. PMID: 33213920
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Atenolol-d7, 25 mg

sc-217669
25 mg
$520.00