Date published: 2025-10-16

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Asterric acid (CAS 577-64-0)

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Application:
Asterric acid is an antibiotic, fungal metabolite
CAS Number:
577-64-0
Molecular Weight:
348.30
Molecular Formula:
C17H16O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Asterric acid is a compound that functions as a potent inhibitor of certain enzymes involved in cellular processes. It exerts its mechanism of action by binding to the active site of the target enzyme, thereby preventing the substrate from binding and inhibiting the enzymatic activity. This inhibition disrupts specific biochemical pathways, leading to downstream effects on cellular function. Asterric acid′s mechanism of action involves interfering with the catalytic activity of the enzyme, ultimately impacting the cellular processes in which the enzyme is involved. Asterric Acid′s ability to selectively inhibit these enzymes may be useful for studying the roles of these enzymes in various cellular pathways. Its mechanism of action at the molecular level provides insights into the specific functions of the targeted enzymes, contributing to a better understanding of cellular processes.


Asterric acid (CAS 577-64-0) References

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  2. Asterric acid, a new endothelin binding inhibitor.  |  Ohashi, H., et al. 1992. J Antibiot (Tokyo). 45: 1684-5. PMID: 1473998
  3. Cyclopentenones, scaffolds for organic syntheses produced by the endophytic fungus mitosporic dothideomycete sp. LRUB20.  |  Chomcheon, P., et al. 2006. J Nat Prod. 69: 1351-3. PMID: 16989533
  4. A new spiroketal from Aspergillus terreus, an endophytic fungus in Opuntia ficusindica Mill.  |  Wu, SH., et al. 2008. J Basic Microbiol. 48: 140-2. PMID: 18383227
  5. Bioactive asterric acid derivatives from the Antarctic ascomycete fungus Geomyces sp.  |  Li, Y., et al. 2008. J Nat Prod. 71: 1643-6. PMID: 18720971
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  7. New species in Aspergillus section Terrei.  |  Samson, RA., et al. 2011. Stud Mycol. 69: 39-55. PMID: 21892242
  8. A new diphenyl ether from Phoma sp. strain, SHZK-2.  |  Fang, MJ., et al. 2012. Nat Prod Res. 26: 1224-8. PMID: 22044095
  9. Two new secondary metabolites from the mangrove endophytic fungus Pleosporales sp. SK7.  |  Wen, S., et al. 2020. Nat Prod Res. 34: 2919-2925. PMID: 30966793
  10. Evaluating the outcomes of submerged co-cultivation: production of lovastatin and other secondary metabolites by Aspergillus terreus in fungal co-cultures.  |  Boruta, T., et al. 2019. Appl Microbiol Biotechnol. 103: 5593-5605. PMID: 31098686
  11. Anti-Inflammatory and Protein Tyrosine Phosphatase 1B Inhibitory Metabolites from the Antarctic Marine-Derived Fungal Strain Penicillium glabrum SF-7123.  |  Ha, TM., et al. 2020. Mar Drugs. 18: PMID: 32397523
  12. Confrontation between Penicillium rubens and Aspergillus terreus: Investigating the production of fungal secondary metabolites in submerged co-cultures.  |  Boruta, T., et al. 2020. J Biosci Bioeng. 130: 503-513. PMID: 32758403
  13. Exploring the extremes: applying high concentration of yeast extract leads to drastic morphological changes and elimination of (+)-geodin and asterric acid production in Aspergillus terreus submerged cultures.  |  Boruta, T., et al. 2021. Biotechnol Lett. 43: 61-71. PMID: 33026584
  14. Isolation and acetylcholinesterase inhibitory activity of asterric acid derivatives produced by Talaromyces aurantiacus FL15, an endophytic fungus from Huperzia serrata.  |  Xiao, Y., et al. 2022. 3 Biotech. 12: 60. PMID: 35186657
  15. Studies in the biochemistry of micro-organisms. 115. Metabolites of Penicillium frequentans Westling: isolation of sulochrin, asterric acid, (+)-bisdechlorogeodin and two new substituted anthraquinones, questin and questinol.  |  Mahmoodian, A. and Stickings, CE. 1964. Biochem J. 92: 369-78. PMID: 5838081

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Asterric acid, 1 mg

sc-202474
1 mg
$192.00