Molecular structure of AST 1306, CAS Number: 1050500-29-2
AST 1306 (CAS 1050500-29-2)
Alternate Names:
AST-6; AST1306 (p-Toluenesulfonic acid); AST 1306 (p-Toluenesulfonic acid)
Application:
AST 1306 is a potent and selective inhibitor of EGFR phosphorylation
CAS Number:
1050500-29-2
Molecular Weight:
621.08
Molecular Formula:
C24H18ClFN4O2•C7H8O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
AST 1306 is a potent(pM) and selective inhibitor of EGFR and ErbB4 (IC50 = 500pM and 800 pM, respectively). AST 1306 blocks phosphorylation of EGFR and also prevents downstream pathways. AST 1306 also dose-dependently inhibits EGF-induced EGFR phosphorylation in the A549 cancer cell line.
AST 1306 (CAS 1050500-29-2) References
1. Xie H, et al. PLoS One. 2011, 6(7), e21487.Inhibitor of:
EGFR, and ErbB-4.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AST 1306, 5 mg | sc-364413 | 5 mg | $420.00 | |||
AST 1306, 10 mg | sc-364413A | 10 mg | $600.00 |