Molecular structure of Aspoxicillin, CAS Number: 63358-49-6
Aspoxicillin (CAS 63358-49-6)
CAS Number:
63358-49-6
Molecular Weight:
493.53
Molecular Formula:
C21H27N5O7S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Aspoxicillin, a peptide, is a potent broad-spectrum antibiotic derived from penicillin. It exhibits remarkable antibacterial activity by binding to and deactivating penicillin-binding proteins (PBPs) situated on the inner membrane of bacterial cell walls. The inhibition of PBPs disrupts the cross-linkage of peptidoglycan chains, essential for maintaining the strength and rigidity of the cell wall. Consequently, bacterial cell wall synthesis is impeded, leading to gradual weakening and eventual lysis of the bacterial cells.
Aspoxicillin (CAS 63358-49-6) References
- Morphological changes and lysis induced by beta-lactams associated with the characteristic profiles of affinities of penicillin-binding proteins in actinobacillus pleuropneumoniae. | Inui, T., et al. 2000. Antimicrob Agents Chemother. 44: 1518-23. PMID: 10817702
- Comparative in vitro activity of 16 antimicrobial agents against Actinobacillus pleuropneumoniae. | Yoshimura, H., et al. 2002. Vet Res Commun. 26: 11-9. PMID: 11860083
- Activity of sub-minimal inhibitory concentrations of aspoxicillin in prolonging the postantibiotic effect against Staphylococcus aureus. | Oshida, T., et al. 1990. J Antimicrob Chemother. 26: 29-38. PMID: 2211444
- Separation and determination of aspoxicillin in human plasma by micellar electrokinetic chromatography with direct sample injection. | Nishi, H., et al. 1990. J Chromatogr. 515: 245-55. PMID: 2283365
- An experimental meningitis with Streptococcus pneumoniae in rats: therapeutic effect of aspoxicillin and its penetration into CSF. | Yamaguchi, T., et al. 1989. Drugs Exp Clin Res. 15: 297-301. PMID: 2591300
- A new model of bacterial peritonitis in mice for evaluation of antibiotics. Effects of aspoxicillin and piperacillin. | Matsushita, T., et al. 1989. Jpn J Antibiot. 42: 887-95. PMID: 2671425
- Therapeutic effect of aspoxicillin on experimental pneumonia with Klebsiella pneumoniae in mice. | Yamaguchi, T., et al. 1989. Drugs Exp Clin Res. 15: 291-6. PMID: 2686954
- Pharmacokinetics of aspoxicillin in subjects with normal and impaired renal function. | Geyer, J., et al. 1988. Arzneimittelforschung. 38: 1635-9. PMID: 3214450
- Determination of aspoxicillin (TA-058) by high-performance liquid chromatography. Stability at different temperatures. | Knöller, J., et al. 1987. Zentralbl Bakteriol Mikrobiol Hyg A. 265: 176-81. PMID: 3673331
- [Clinical and laboratory evaluation of aspoxicillin in the pediatric field]. | Nishimura, T., et al. 1985. Jpn J Antibiot. 38: 1889-97. PMID: 3851861
- [The therapeutic effects of aspoxicillin on various infectious diseases in children]. | Wakiguchi, H., et al. 1985. Jpn J Antibiot. 38: 1925-30. PMID: 4068226
- [Safety and pharmacology of aspoxicillin in healthy volunteers]. | Matsumoto, K., et al. 1985. Jpn J Antibiot. 38: 2699-715. PMID: 4078992
- Determination of aspoxicillin in broncho-alveolar lavage fluid by high-performance liquid chromatography with photolysis and electrochemical detection. | Yamazaki, T., et al. 1993. J Chromatogr. 615: 180-5. PMID: 8340459
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aspoxicillin, 25 mg | sc-233895 | 25 mg | $181.00 |