Date published: 2026-5-3

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Aspergillin PZ (CAS 483305-08-4)

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Application:
Aspergillin PZ is A secondary metabolite with anti-tumor properties
CAS Number:
483305-08-4
Molecular Weight:
401.60
Molecular Formula:
C24H35NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Aspergillin PZ is a secondary metabolite of Aspergillus awamori capable of inducing deformities in the conidia of P. oryzae. Aspergillin PZ may possess anti-cancer and anti-tumor properties.


Aspergillin PZ (CAS 483305-08-4) References

  1. Aspergillin PZ, a novel isoindole-alkaloid from Aspergillus awamori.  |  Zhang, Y., et al. 2002. J Antibiot (Tokyo). 55: 693-5. PMID: 12374381
  2. Identification of an Unexpected 2-Oxonia[3,3]sigmatropic Rearrangement/Aldol Pathway in the Formation of Oxacyclic Rings. Total Synthesis of (+)-Aspergillin PZ.  |  Canham, SM., et al. 2011. Tetrahedron. 67: 9837-9843. PMID: 22518066
  3. Stereochemical determination of new cytochalasans from the plant endophytic fungus Trichoderma gamsii.  |  Chen, L., et al. 2014. Fitoterapia. 96: 115-22. PMID: 24752139
  4. Flavichalasines A-M, cytochalasan alkaloids from Aspergillus flavipes.  |  Wei, G., et al. 2017. Sci Rep. 7: 42434. PMID: 28205583
  5. Biomimetic Synthesis of (+)-Aspergillin PZ.  |  Reyes, JR., et al. 2018. Angew Chem Int Ed Engl. 57: 15587-15591. PMID: 30239081
  6. Two Novel Aspochalasins from the Gut Fungus Aspergillus sp. Z4.  |  Li, X., et al. 2018. Mar Drugs. 16: PMID: 30241299
  7. Bioinspired Network Analysis Enabled Divergent Syntheses and Structure Revision of Pentacyclic Cytochalasans.  |  Wu, H., et al. 2021. Angew Chem Int Ed Engl. 60: 15963-15971. PMID: 33860618
  8. Berberine bridge enzyme-like oxidase-catalysed double bond isomerization acts as the pathway switch in cytochalasin synthesis.  |  Zhang, JM., et al. 2022. Nat Commun. 13: 225. PMID: 35017571
  9. Insights into the Chemical Diversity of Selected Fungi from the Tza Itzá Cenote of the Yucatan Peninsula.  |  Fajardo-Hernández, CA., et al. 2022. ACS Omega. 7: 12171-12185. PMID: 35449929
  10. Antitumor aspochalasin and antiviral benzofuran derivatives from a marine-derived fungus Aspergillus sp. SCSIO41032.  |  Chen, W., et al. 2024. Nat Prod Res. 1-8. PMID: 38853392

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Aspergillin PZ, 1 mg

sc-396535
1 mg
$124.00