Date published: 2025-11-1

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Aspartame (CAS 22839-47-0)

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Alternate Names:
L-α-Aspartyl-L-phenylalanine 2-Methyl Ester; Canderel
Application:
Aspartame is a dipeptide ester
CAS Number:
22839-47-0
Purity:
≥98%
Molecular Weight:
294.30
Molecular Formula:
C14H18N2O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Aspartame (APM) is a widely used artificial sweetener employed in various food products and beverages. Being a low-calorie alternative, it possesses a sweetness that is approximately 200 times stronger than that of sugar. Comprising a dipeptide consisting of aspartic acid and phenylalanine, it is a safe and effective substitute for sugar and other artificial sweeteners. Aspartame finds utility in diverse scientific research applications, encompassing in vitro studies. In vitro studies take place within laboratory applications using test tubes and similar environments.


Aspartame (CAS 22839-47-0) References

  1. Effects of aspartame metabolites on astrocytes and neurons.  |  Rycerz, K. and Jaworska-Adamu, JE. 2013. Folia Neuropathol. 51: 10-7. PMID: 23553132
  2. Aspartame and Risk of Cancer: A Meta-analytic Review.  |  Mallikarjun, S. and Sieburth, RM. 2015. Arch Environ Occup Health. 70: 133-41. PMID: 24965331
  3. Neurophysiological symptoms and aspartame: What is the connection?  |  Choudhary, AK. and Lee, YY. 2018. Nutr Neurosci. 21: 306-316. PMID: 28198207
  4. Metabolic effects of aspartame in adulthood: A systematic review and meta-analysis of randomized clinical trials.  |  Santos, NC., et al. 2018. Crit Rev Food Sci Nutr. 58: 2068-2081. PMID: 28394643
  5. Aspartame: Should Individuals with Type II Diabetes be Taking it?  |  Choudhary, AK. 2018. Curr Diabetes Rev. 14: 350-362. PMID: 28571543
  6. Revisiting the safety of aspartame.  |  Choudhary, AK. and Pretorius, E. 2017. Nutr Rev. 75: 718-730. PMID: 28938797
  7. Nephrotoxic Effect of Aspartame as an Artificial Sweetener: a Brief Review.  |  Ardalan, MR., et al. 2017. Iran J Kidney Dis. 11: 339-343. PMID: 29038387
  8. Mutagenicity and genotoxicity studies of aspartame.  |  Otabe, A., et al. 2019. Regul Toxicol Pharmacol. 103: 345-351. PMID: 29408486
  9. Health Implications Associated with Aspartame Consumption: A Substantial Review.  |  Naik, AQ., et al. 2018. Pak J Biol Sci. 21: 127-134. PMID: 30187722
  10. Effect of sucralose and aspartame on glucose metabolism and gut hormones.  |  Ahmad, SY., et al. 2020. Nutr Rev. 78: 725-746. PMID: 32065635
  11. Aspartame and cancer - new evidence for causation.  |  Landrigan, PJ. and Straif, K. 2021. Environ Health. 20: 42. PMID: 33845854
  12. Aspartame-True or False? Narrative Review of Safety Analysis of General Use in Products.  |  Czarnecka, K., et al. 2021. Nutrients. 13: PMID: 34200310
  13. Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala.  |  Jones, SK., et al. 2022. Proc Natl Acad Sci U S A. 119: e2213120119. PMID: 36459641

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Aspartame, 1 g

sc-210840
1 g
$55.00