Molecular structure of Asiaticoside, CAS Number: 16830-15-2
Asiaticoside (CAS 16830-15-2)
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Alternate Names:
Asiaticoside is also known as Madecassol
Application:
Asiaticoside is a saponin with significant wound and burn healing activity, used to study potential treatments.
CAS Number:
16830-15-2
Purity:
≥97%
Molecular Weight:
959.12
Molecular Formula:
C48H78O19
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Asiaticoside is a triterpene glycoside compound that has attention in botanical and biochemical research. It is studied for its role in plant defense mechanisms and as a bioactive compound. Asiaticoside is found in the plant Centella asiatica, and its effects on cellular and molecular processes are a subject of investigation. In a research context, asiaticoside is analyzed for its potential to stimulate collagen production and promote fibroblast proliferation. Research also examines how asiaticoside can scavenge free radicals and contribute to the plant′s protective responses against oxidative stress. Furthermore, the compound is a point of interest in the study of signaling pathways involved in skin repair and regeneration.
Asiaticoside (CAS 16830-15-2) References
- The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats. | Cheng, CL., et al. 2004. Life Sci. 74: 2237-49. PMID: 14987949
- Stimulation of asiaticoside accumulation in the whole plant cultures of Centella asiatica (L.) urban by elicitors. | Kim, OT., et al. 2004. Plant Cell Rep. 23: 339-44. PMID: 15316748
- Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblasts. | Lu, L., et al. 2004. Int J Dermatol. 43: 801-7. PMID: 15533060
- Evaluation of anxiolytic properties of Gotukola--(Centella asiatica) extracts and asiaticoside in rat behavioral models. | Wijeweera, P., et al. 2006. Phytomedicine. 13: 668-76. PMID: 16488124
- Asiaticoside induces human collagen I synthesis through TGFbeta receptor I kinase (TbetaRI kinase)-independent Smad signaling. | Lee, J., et al. 2006. Planta Med. 72: 324-8. PMID: 16557473
- Facilitating action of asiaticoside at low doses on burn wound repair and its mechanism. | Kimura, Y., et al. 2008. Eur J Pharmacol. 584: 415-23. PMID: 18353310
- Enrichment and purification of madecassoside and asiaticoside from Centella asiatica extracts with macroporous resins. | Jia, G. and Lu, X. 2008. J Chromatogr A. 1193: 136-41. PMID: 18457845
- Electrospun gelatin fiber mats containing a herbal-Centella asiatica-extract and release characteristic of asiaticoside. | Sikareepaisan, P., et al. 2008. Nanotechnology. 19: 015102. PMID: 21730522
- Asiaticoside enhances normal human skin cell migration, attachment and growth in vitro wound healing model. | Lee, JH., et al. 2012. Phytomedicine. 19: 1223-7. PMID: 22939261
- Study of the cytotoxicity of asiaticoside on rats and tumour cells. | Al-Saeedi, FJ. 2014. BMC Cancer. 14: 220. PMID: 24667059
- Nerve Protective Effect of Asiaticoside against Ischemia-Hypoxia in Cultured Rat Cortex Neurons. | Sun, T., et al. 2015. Med Sci Monit. 21: 3036-41. PMID: 26447863
- Asiaticoside attenuates hyperoxia-induced lung injury in vitro and in vivo. | Dang, JW., et al. 2019. Iran J Basic Med Sci. 22: 797-805. PMID: 32373302
- Asiaticoside produces an antidepressant‑like effect in a chronic unpredictable mild stress model of depression in mice, involving reversion of inflammation and the PKA/pCREB/BDNF signaling pathway. | Wang, L., et al. 2020. Mol Med Rep. 22: 2364-2372. PMID: 32705202
- Influence of asiatic acid, madecassic acid, and asiaticoside on human collagen I synthesis. | Bonte, F., et al. 1994. Planta Med. 60: 133-5. PMID: 8202564
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CD30.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Asiaticoside, 5 mg | sc-257101 | 5 mg | $112.00 | |||
Asiaticoside, 25 mg | sc-257101A | 25 mg | $203.00 | |||
Asiaticoside, 100 mg | sc-257101B | 100 mg | $617.00 | |||
Asiaticoside, 1 g | sc-257101C | 1 g | $1121.00 | |||
Asiaticoside, 10 g | sc-257101D | 10 g | $4079.00 |