Molecular structure of Artemisinin, CAS Number: 63968-64-9
Artemisinin (CAS 63968-64-9)
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Alternate Names:
Arteannuin; Qinghaosu
Application:
Artemisinin is an antimalarial agent that inhibits VEGF expression and NOS2
CAS Number:
63968-64-9
Purity:
>98%
Molecular Weight:
282.33
Molecular Formula:
C15H22O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Artemisinin is a sesquiterpene lactone compound. Artemisinin works by targeting the iron-containing heme molecules within the malaria parasite, leading to the production of toxic free radicals that ultimately kill the parasite. Artemisinin has a unique chemical structure that allows it to effectively penetrate the infected red blood cells and exert its antimalarial activity.
Artemisinin (CAS 63968-64-9) References
- Artemisinin: mechanisms of action, resistance and toxicity. | Meshnick, SR. 2002. Int J Parasitol. 32: 1655-60. PMID: 12435450
- Artemisinin-A Gift from Traditional Chinese Medicine to the World (Nobel Lecture). | Tu, Y. 2016. Angew Chem Int Ed Engl. 55: 10210-26. PMID: 27488942
- Unpacking 'Artemisinin Resistance'. | Wang, J., et al. 2017. Trends Pharmacol Sci. 38: 506-511. PMID: 28473165
- Artemisinin Bioactivity and Resistance in Malaria Parasites. | Talman, AM., et al. 2019. Trends Parasitol. 35: 953-963. PMID: 31699532
- Artemisinin-derived dimers as potential anticancer agents: Current developments, action mechanisms, and structure-activity relationships. | Zhang, B. 2020. Arch Pharm (Weinheim). 353: e1900240. PMID: 31797422
- Parallel Transcriptional Regulation of Artemisinin and Flavonoid Biosynthesis. | Hassani, D., et al. 2020. Trends Plant Sci. 25: 466-476. PMID: 32304658
- Artemisinin and its derivatives: a promising cancer therapy. | Kiani, BH., et al. 2020. Mol Biol Rep. 47: 6321-6336. PMID: 32710388
- The birth of artemisinin. | Ma, N., et al. 2020. Pharmacol Ther. 216: 107658. PMID: 32777330
- Drug-induced hypersensitivity to artemisinin-based therapies for malaria. | Nordmann, T., et al. 2022. Trends Parasitol. 38: 136-146. PMID: 34561157
- Artemisinin resistance: an important emerging clinical problem in tropical medicine. | Yasri, S. and Wiwanitkit, V. 2021. Int J Physiol Pathophysiol Pharmacol. 13: 152-157. PMID: 35103097
- Discovery and repurposing of artemisinin. | Shi, Q., et al. 2022. Front Med. 16: 1-9. PMID: 35290595
- Artemisinin resistance and malaria elimination: Where are we now? | Hanboonkunupakarn, B., et al. 2022. Front Pharmacol. 13: 876282. PMID: 36210819
- From Plant to Yeast-Advances in Biosynthesis of Artemisinin. | Zhao, L., et al. 2022. Molecules. 27: PMID: 36296479
Inhibitor of:
Forkhead box N (FOXN), HRP-2, NOS2, P. falciparum infected RBCs, Plasmodium falciparum, StARD13, V1RF2, and V1RF3.Activator of:
ASB-12, MB67_CAR1/2, MOAP1, and RBP-Jκ.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Artemisinin, 100 mg | sc-202960 | 100 mg | $44.00 | |||
Artemisinin, 1 g | sc-202960A | 1 g | $247.00 |