Date published: 2026-5-18

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Arsenobetaine (CAS 64436-13-1)

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Alternate Names:
2-(Trimethylarsonio)acetate
Application:
Arsenobetaine is a chemical used to study arsenic in proteomics research
CAS Number:
64436-13-1
Purity:
≥95%
Molecular Weight:
178.06
Molecular Formula:
C5H11AsO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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In scientific investigations, arsenobetaine′s presence in marine life is utilized to explore the broader impacts of arsenic compounds that are toxic. Research involving arsenobetaine also encompasses the examination of how arsenic accumulates in aquatic organisms and its subsequent transport and metabolic pathways. Additionally, studies involving arsenobetaine contribute to understanding the environmental trajectory of arsenic in marine ecosystems. Arsenobetaine binds with cellular proteins and nucleic acids, as well as potentially forming complexes with sulfhydryl groups on proteins.


Arsenobetaine (CAS 64436-13-1) References

  1. Bacterial degradation of arsenobetaine via dimethylarsinoylacetate.  |  Jenkins, RO., et al. 2003. Arch Microbiol. 180: 142-50. PMID: 12827219
  2. Arsenobetaine in Atlantic salmon (Salmo salar L.): influence of seawater adaptation.  |  Amlund, H. and Berntssen, MH. 2004. Comp Biochem Physiol C Toxicol Pharmacol. 138: 507-14. PMID: 15536058
  3. Cellular retention, toxicity and carcinogenic potential of seafood arsenic. I. Lack of cytotoxicity and transforming activity of arsenobetaine in the BALB/3T3 cell line.  |  Sabbioni, E., et al. 1991. Carcinogenesis. 12: 1287-91. PMID: 2070494
  4. Humans seem to produce arsenobetaine and dimethylarsinate after a bolus dose of seafood.  |  Molin, M., et al. 2012. Environ Res. 112: 28-39. PMID: 22137101
  5. Comparative contribution of trophic transfer and biotransformation on arsenobetaine bioaccumulation in two marine fish.  |  Zhang, W., et al. 2016. Aquat Toxicol. 179: 65-71. PMID: 27584085
  6. Arsenobetaine: an ecophysiologically important organoarsenical confers cytoprotection against osmotic stress and growth temperature extremes.  |  Hoffmann, T., et al. 2018. Environ Microbiol. 20: 305-323. PMID: 29159878
  7. Arsenobetaine in Seawater: Depth Profiles from Selected Sites in the North Atlantic.  |  Glabonjat, RA., et al. 2018. Environ Sci Technol. 52: 522-530. PMID: 29232115
  8. Identification of Arctic Food Fish Species for Anthropogenic Contaminant Testing Using Geography and Genetics.  |  Walker, VK., et al. 2020. Foods. 9: PMID: 33302601
  9. Biodegradation of arsenobetaine to inorganic arsenic regulated by specific microorganisms and metabolites in mice.  |  Ye, Z., et al. 2022. Toxicology. 475: 153238. PMID: 35718002
  10. Key genes for arsenobetaine synthesis in marine medaka (Oryzias melastigma) by transcriptomics.  |  Ye, Z., et al. 2022. Aquat Toxicol. 253: 106349. PMID: 36395554
  11. Significant Biotransformation of Arsenobetaine into Inorganic Arsenic in Mice.  |  Zhang, J., et al. 2023. Toxics. 11: PMID: 36850967
  12. Metabolism of arsenobetaine in mice, rats and rabbits.  |  Vahter, M., et al. 1983. Sci Total Environ. 30: 197-211. PMID: 6648507
  13. Arsenobetaine is not a major metabolite of arsine gas in the rat.  |  Buchet, JP., et al. 1998. Arch Toxicol. 72: 706-10. PMID: 9879808

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Arsenobetaine, 50 mg

sc-227279
50 mg
$449.00