Date published: 2025-12-6

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Arphamenine B (CAS 144110-38-3)

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Alternate Names:
5-amino-8-guanidino-2-(4-hydroxyphenylmethyl)-4-oxooctanoic acid
Application:
Arphamenine B is a specific aminopeptidase B inhibitor
CAS Number:
144110-38-3
Molecular Weight:
385.43
Molecular Formula:
C16H24N4O40.5H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Arphamenine B is a compound of interest in biochemical research due to its unique mechanism as an inhibitor of aminopeptidase B, an enzyme involved in protein and peptide metabolism. This characteristic makes arphamenine B useful for probing the role of aminopeptidase B in biological processes, including protein degradation and hormone regulation. Its inhibitory properties are also leveraged in enzymology studies to better understand the substrate specificity and catalytic mechanisms of this class of enzymes. In plant biology, researchers investigate arphamenine B′s effects on various physiological processes, considering its potential to modulate peptide-mediated signaling pathways. Its ability to influence aminopeptidase activity has implications for research into metabolic pathways and can provide insights into the development of novel research tools for biotechnology applications.


Arphamenine B (CAS 144110-38-3) References

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  2. Two broad-specificity dipeptide hydrolysing activities from cytoplasm of guinea pig brain, both of which contain prolinase but neither of which contain carnosinase activity.  |  Keane, F. and O'Cuinn, G. 2002. Neurosci Res. 44: 111-20. PMID: 12204299
  3. Zinc regulation of aminopeptidase B involved in neuropeptide production.  |  Hwang, SR. and Hook, V. 2008. FEBS Lett. 582: 2527-31. PMID: 18571504
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  14. Purification and properties of a membrane aminopeptidase from Ascaris suum muscle that degrades neuropeptides AF1 and AF2.  |  Sajid, M., et al. 1997. Mol Biochem Parasitol. 89: 225-34. PMID: 9364967

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Arphamenine B, 1 mg

sc-202959
1 mg
$39.00

Arphamenine B, 5 mg

sc-202959A
5 mg
$147.00