Date published: 2025-12-15

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Arjunolic acid (CAS 465-00-9)

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Datasheets
Alternate Names:
Urjinolic acid
Application:
Arjunolic acid is a pentacyclic triterpenoid
CAS Number:
465-00-9
Purity:
≥95%
Molecular Weight:
460.70
Molecular Formula:
C30H48O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Arjunolic acid is a triterpenoid saponin derived from the bark of the Terminalia arjuna tree, notable for its distinct pentacyclic structure which imparts significant antioxidant properties. This compound is renowned in the field of organic chemistry for its potent ability to scavenge free radicals and chelate metal ions, mechanisms that are crucial in mitigating oxidative stress within biological systems. Researchers have leveraged arjunolic acid in various studies to explore its protective effects against oxidative damage in cellular components, which is fundamental in the aging process and the development of chronic diseases. Beyond its basic antioxidant activity, arjunolic acid has been instrumental in biochemical research aimed at understanding how it interacts with cellular membranes and proteins, offering insights into the stabilization of cellular structures and the prevention of oxidative deterioration. This research has broad implications, extending arjunolic acid′s utility to industrial applications, including food preservation and the formulation of health supplements, where its natural antioxidant properties can be effectively harnessed to enhance product stability and enrich nutritional content, thereby contributing to the field of natural product chemistry and its practical applications in commercial products.


Arjunolic acid (CAS 465-00-9) References

  1. Arjunolic acid: a novel phytomedicine with multifunctional therapeutic applications.  |  Hemalatha, T., et al. 2010. Indian J Exp Biol. 48: 238-47. PMID: 21046976
  2. Arjunolic acid: beneficial role in type 1 diabetes and its associated organ pathophysiology.  |  Manna, P. and Sil, PC. 2012. Free Radic Res. 46: 815-30. PMID: 22486656
  3. Arjunolic acid: a new multifunctional therapeutic promise of alternative medicine.  |  Ghosh, J. and Sil, PC. 2013. Biochimie. 95: 1098-109. PMID: 23402784
  4. Arjunolic Acid Improves the Serum Level of Vitamin B12 and Folate in the Process of the Attenuation of Arsenic Induced Uterine Oxidative Stress.  |  Maity, M., et al. 2018. Biol Trace Elem Res. 182: 78-90. PMID: 28660490
  5. Arjunolic acid from Cyclocarya paliurus ameliorates diabetic retinopathy through AMPK/mTOR/HO-1 regulated autophagy pathway.  |  Zhang, XX., et al. 2022. J Ethnopharmacol. 284: 114772. PMID: 34688801
  6. Arjunolic acid downregulates elevated blood sugar and pro-inflammatory cytokines in streptozotocin (STZ)-nicotinamide induced type 2 diabetic rats.  |  Aamir, K., et al. 2022. Life Sci. 289: 120232. PMID: 34919901
  7. Arjunolic acid modulate pancreatic dysfunction by ameliorating pattern recognition receptor and canonical Wnt pathway activation in type 2 diabetic rats.  |  Aamir, K., et al. 2023. Life Sci. 327: 121856. PMID: 37307966
  8. Cardioprotective effects of arjunolic acid in LPS-stimulated H9C2 and C2C12 myotubes via the My88-dependent TLR4 signaling pathway.  |  Hasan, MM., et al. 2023. Pharm Biol. 61: 1135-1151. PMID: 37497554
  9. Arjunolic acid protects the intestinal epithelial barrier, ameliorating Crohn's disease-like colitis by restoring gut microbiota composition and inactivating TLR4 signalling.  |  Zhang, Z., et al. 2024. Phytomedicine. 123: 155223. PMID: 38134862
  10. Arjunolic acid ameliorates lipopolysaccharide-induced depressive behavior by inhibiting neuroinflammation via microglial SIRT1/AMPK/Notch1 signaling pathway.  |  Yang, Y., et al. 2024. J Ethnopharmacol. 330: 118225. PMID: 38670408

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Arjunolic acid, 1 mg

sc-506421
1 mg
$272.00

Arjunolic acid, 5 mg

sc-506421A
5 mg
$770.00