Arginine Antibody (7E6): sc-57626
- Arginine Antibody (7E6) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µl ascites
- raised against asymmetric NG-NG-dimethyl arginine
- recommended for detection of free and bound NG-NG-dimethyl Arginine by WB and IF; may cross-react with free and bound asymmetric NG-monomethyl Arginine; non cross-reactive with unmodified free or bound Arginine
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Arginine Antibody (7E6). This work is in progress.
QUICK LINKS
SEE ALSO...
Arginine Antibody (7E6) is a mouse monoclonal IgG1 antibody that detects Arginine in non-species reactive applications such as western blotting (WB) and immunofluorescence (IF). Anti-Arginine antibody (7E6) is available in a non-conjugated form, specifically designed for researchers seeking to study the dynamics of Arginine in various biological contexts. Arginine is an essential α-amino acid that plays a critical role in numerous physiological processes, including protein synthesis, cell division, and immune response. Notably, Arginine is a precursor for nitric oxide, a vital signaling molecule involved in vasodilation and neurotransmission, highlighting its importance in cardiovascular health and neurological function. Arginine is primarily located in the cytoplasm and is involved in the urea cycle, where Arginine helps in the detoxification of ammonia, a byproduct of protein metabolism. This localization is crucial as Arginine participates in metabolic pathways that maintain nitrogen balance in the body. Furthermore, Arginine′s unique structure, characterized by its long side chain and positively charged guanidinium group, enables Arginine to interact with various proteins and enzymes, facilitating essential biochemical reactions. Arginine′s ability to form hydrogen bonds enhances solubility and reactivity, making Arginine a key player in cellular signaling and metabolic regulation.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Arginine Antibody (7E6) References:
- Arginine and nitric oxide metabolism in critically ill septic pediatric patients. | Argaman, Z., et al. 2003. Crit Care Med. 31: 591-7. PMID: 12576971
- Enzymes of arginine metabolism. | Morris, SM. 2004. J Nutr. 134: 2743S-2747S; discussion 2765S-2767S. PMID: 15465778
- Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock? | Thompson, PR. and Fast, W. 2006. ACS Chem Biol. 1: 433-41. PMID: 17168521
- Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate. | Marletta, MA., et al. 1988. Biochemistry. 27: 8706-11. PMID: 3242600
- Plasma arginine kinetics in adult man: response to an arginine-free diet. | Castillo, L., et al. 1994. Metabolism. 43: 114-22. PMID: 8289668
- Splanchnic metabolism of dietary arginine in relation to nitric oxide synthesis in normal adult man. | Castillo, L., et al. 1993. Proc Natl Acad Sci U S A. 90: 193-7. PMID: 8419922
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Arginine Antibody (7E6) | sc-57626 | 100 µl ascites | $339.00 |