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ARF1 Antibody (ARFS 5F2/2) is a mouse monoclonal IgM antibody that detects ARF1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARF1 is a crucial member of the ADP-ribosylation factor family, which plays a significant role in vesicular transport and membrane trafficking within eukaryotic cells. ARF1 is primarily located at the Golgi membrane, where ARF1 is involved in the recruitment of coatomer protein complex I (COPI), a heptameric protein essential for the formation of transport vesicles. The interaction between ARF1 and COPI is vital for maintaining organelle integrity and facilitating the proper distribution of proteins and lipids throughout the cell. Additionally, ARF1 is regulated by the binding and hydrolysis of guanosine triphosphate (GTP), which activates ARF1 function and allows for effective mediation of membrane dynamics. The ability of ARF1 to reversibly associate with membranes and interact with specific phospholipids underscores ARF1′s importance in cellular processes, making anti-ARF1 antibody (ARFS 5F2/2) an invaluable tool for researchers studying membrane trafficking and related pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARF1 Antibody (ARFS 5F2/2) | sc-53169 | 200 µg/ml | $322.00 |