Arecoline hydrobromide (CAS 300-08-3)
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Arecoline hydrobromide is a compound used in neuroscience and cognitive research due to its activity as a muscarinic acetylcholine receptor agonist. This activity makes it useful for studying cholinergic neurotransmission and its effects on cognitive functions and behavior in various experimental models. In addition, Arecoline hydrobromide is used in the investigation of memory and learning processes, as the modulation of muscarinic receptors is known to play a role in these neural activities. It is also applied in studies that explore the signaling mechanisms underlying muscarinic receptor activation and the subsequent cellular responses. Furthermore, researchers utilize Arecoline hydrobromide in agricultural studies to understand the biological effects of areca nut components on pest organisms.
Arecoline hydrobromide (CAS 300-08-3) References
- Teratogenicity of arecoline hydrobromide on developing chick embryos: a preliminary report. | Paul, K., et al. 1999. Bull Environ Contam Toxicol. 62: 356-62. PMID: 10085181
- Comparative value of arecoline hydrobromide and bunamidine hydrochloride for the treatment of Echinococcus granulosus in dogs. | Trejos, A., et al. 1975. Res Vet Sci. 19: 212-3. PMID: 1172623
- Arecoline, but not haloperidol, induces changes in the permeability of the blood-brain barrier in the rat. | Saija, A., et al. 1990. J Pharm Pharmacol. 42: 135-8. PMID: 1972401
- Frequency- and state-dependent blockade of human ether-a-go-go-related gene K+ channel by arecoline hydrobromide. | Zhao, XY., et al. 2012. Chin Med J (Engl). 125: 1068-75. PMID: 22613533
- A protective role of arecoline hydrobromide in experimentally induced male diabetic rats. | Saha, I., et al. 2015. Biomed Res Int. 2015: 136738. PMID: 25695047
- Evaluation of arecoline hydrobromide toxicity after a 14-day repeated oral administration in Wistar rats. | Wei, X., et al. 2015. PLoS One. 10: e0120165. PMID: 25880067
- Arecoline attenuates memory impairment and demyelination in a cuprizone-induced mouse model of schizophrenia. | Xu, Z., et al. 2019. Neuroreport. 30: 134-138. PMID: 30571667
- Arecoline hydrobromide enhances jejunum smooth muscle contractility via voltage-dependent potassium channels in W/Wv mice. | Chen, Q., et al. 2021. Physiol Res. 70: 437-446. PMID: 33982580
- Acaricidal activity and clinical safety of arecoline hydrobromide on calves infested with cattle tick Rhipicephalus microplus (Acari: Ixodidae). | Jain, P., et al. 2021. Vet Parasitol. 298: 109490. PMID: 34271319
- In Vitro Characterization of Inhibitors for Lung A549 and Leukemia K562 Cell Lines from Fungal Transformation of Arecoline Supported by In Silico Docking to M3-mAChR and ADME Prediction. | Ragab, AE., et al. 2022. Pharmaceuticals (Basel). 15: PMID: 36297282
- Surveillance of Echinococcus granulosus in dogs with arecoline hydrobromide. | Gemmell, MA. 1973. Bull World Health Organ. 48: 649-52. PMID: 4544776
- Activity of uredofos, niclosamide, bunamidine hydrochloride, and arecoline hydrobromide against Mesocestoides corti in experimentally infected dogs. | Todd, KS., et al. 1978. Am J Vet Res. 39: 315-6. PMID: 564650
- The toxicity and efficiency of arecoline hydrobromide in the Tasmanian hydatid control program. | Gregory, GG. and McConnell, JD. 1978. Aust Vet J. 54: 193-5. PMID: 687277
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Arecoline hydrobromide, 5 g | sc-252386 | 5 g | $153.00 |