Molecular structure of Arecaidine propargyl ester hydrobromide, CAS Number: 116511-28-5
Arecaidine propargyl ester hydrobromide (CAS 116511-28-5)
CAS Number:
116511-28-5
Molecular Weight:
260.13
Molecular Formula:
C10H13NO2•HBr
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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A potent muscarinic acetylcholine receptor agonist exhibiting slight selectivity for M2 receptors inactive at nicotinic receptors. Arecaidine propargyl ester hydrobromide, a widely used organic compound in laboratory applications, possesses a colorless and crystalline solid form. Its versatility allows for the synthesis of diverse compounds, including drugs, polymers, and various materials. It has proven valuable in synthesizing small molecules, peptides, and proteins, as well as polymers and other materials. Moreover, this compound has contributed to the examination of protein structure and function, along with the exploration of enzyme kinetics.
Arecaidine propargyl ester hydrobromide (CAS 116511-28-5) References
- The activation of M2 muscarinic receptor inhibits cell growth and survival in human glioblastoma cancer stem cells. | Alessandrini, F., et al. 2015. Int Immunopharmacol. 29: 105-9. PMID: 26033491
- Cytotoxic and genotoxic effects mediated by M2 muscarinic receptor activation in human glioblastoma cells. | Di Bari, M., et al. 2015. Neurochem Int. 90: 261-70. PMID: 26455407
- M2 muscarinic receptor activation inhibits cell proliferation and migration of rat adipose-mesenchymal stem cells. | Piovesana, R., et al. 2018. J Cell Physiol. 233: 5348-5360. PMID: 29227527
- M2 receptors activation modulates cell growth, migration and differentiation of rat Schwann-like adipose-derived stem cells. | Piovesana, R., et al. 2019. Cell Death Discov. 5: 92. PMID: 31069117
- M2 Receptor Activation Counteracts the Glioblastoma Cancer Stem Cell Response to Hypoxia Condition. | Cristofaro, I., et al. 2020. Int J Mol Sci. 21: PMID: 32131421
- Cross Interaction between M2 Muscarinic Receptor and Notch1/EGFR Pathway in Human Glioblastoma Cancer Stem Cells: Effects on Cell Cycle Progression and Survival. | Cristofaro, I., et al. 2020. Cells. 9: PMID: 32182759
- Functional Characterization of Muscarinic Receptors in Human Schwann Cells. | Piovesana, R., et al. 2020. Int J Mol Sci. 21: PMID: 32933046
- The Combination of the M2 Muscarinic Receptor Agonist and Chemotherapy Affects Drug Resistance in Neuroblastoma Cells. | Lucianò, AM., et al. 2020. Int J Mol Sci. 21: PMID: 33182656
- M2 Muscarinic Receptor Activation Impairs Mitotic Progression and Bipolar Mitotic Spindle Formation in Human Glioblastoma Cell Lines. | Di Bari, M., et al. 2021. Cells. 10: PMID: 34359896
- Notch Signal Mediates the Cross-Interaction between M2 Muscarinic Acetylcholine Receptor and Neuregulin/ErbB Pathway: Effects on Schwann Cell Proliferation. | Piovesana, R., et al. 2022. Biomolecules. 12: PMID: 35204740
- Analysis of Signal Transduction Pathways Downstream M2 Receptor Activation: Effects on Schwann Cell Migration and Morphology. | Botticelli, E., et al. 2022. Life (Basel). 12: PMID: 35207498
- The activation of M2 muscarinic receptor inhibits cell growth and survival in human epithelial ovarian carcinoma. | Taggi, M., et al. 2022. J Cell Biochem. 123: 1440-1453. PMID: 35775813
- Characterization of muscarinic receptors mediating vasodilation in rat perfused kidney. | Eltze, M., et al. 1993. Eur J Pharmacol. 238: 343-55. PMID: 8405103
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Arecaidine propargyl ester hydrobromide, 25 mg | sc-257091 | 25 mg | $230.00 |