Date published: 2026-4-30

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Arecaidine hydrochloride (CAS 6018-28-6)

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Alternate Names:
1,2,5,6-Tetrahydro-1-methylnicotinic acid hydrochloride
CAS Number:
6018-28-6
Purity:
97%
Molecular Weight:
177.63
Molecular Formula:
C7H11NO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Arecaidine hydrochloride is a chemical that functions as an inhibitor of acetylcholinesterase, which is an enzyme responsible for breaking down the neurotransmitter acetylcholine. By inhibiting this enzyme, arecaidine hydrochloride increases the levels of acetylcholine in the synaptic cleft, leading to prolonged stimulation of cholinergic receptors. Arecaidine Hydrochloride′s mechanism of action involves binding to the active site of acetylcholinesterase, preventing it from catalyzing the hydrolysis of acetylcholine. As a result, arecaidine hydrochloride can modulate cholinergic neurotransmission and affect various physiological processes that involve acetylcholine signaling. In research and development, this chemical′s function as an acetylcholinesterase inhibitor can be utilized to study the role of acetylcholine in different biological systems.


Arecaidine hydrochloride (CAS 6018-28-6) References

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  2. Characterization of protein adducts formed by toxic alkaloids by nano-scale liquid chromatography with mass spectrometry.  |  Chou, CH., et al. 2012. J Mass Spectrom. 47: 1303-12. PMID: 23019161
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  6. Sub-chronic toxicity study of arecae semen aqueous extract in Wistar rats.  |  Lin, Q., et al. 2018. J Ethnopharmacol. 215: 176-183. PMID: 28847753
  7. Effects of Maerua subcordata (Gilg) DeWolf on electrophile-responsive element (EpRE)-mediated gene expression in vitro.  |  Gebrelibanos Hiben, M., et al. 2019. PLoS One. 14: e0215155. PMID: 30986264
  8. Testing for Betel Nut Alkaloids in Hair of Papuans Abusers using UPLC-MS/MS and UPLC-Q-Tof-MS.  |  Gheddar, L., et al. 2020. J Anal Toxicol. 44: 41-48. PMID: 31263904
  9. HPLC-Based Qualitative and Quantitative Analyses of Alkaloids in Chewable Areca Products from Different Geographic Regions.  |  Cao, M., et al. 2020. J AOAC Int. 103: 1400-1405. PMID: 33241395
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  12. Brain uptake of pipecolic acid, amino acids, amines following intracarotid injection in the mouse.  |  Nishio, H. and Giacobini, E. 1981. Neurochem Res. 6: 835-45. PMID: 6796898
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Arecaidine hydrochloride, 100 mg

sc-233889
100 mg
$104.00

Arecaidine hydrochloride, 1 g

sc-233889A
1 g
$520.00