Date published: 2026-4-5

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Arbutin (CAS 497-76-7)

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Alternate Names:
4-Hydroxyphenyl-β-D-glucopyranoside
Application:
Arbutin is an inhibitor of Tyrosinase
CAS Number:
497-76-7
Purity:
≥98%
Molecular Weight:
272.25
Molecular Formula:
C12H16O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Arbutin is an inhibitor of Tyrosinase. Arbutin, a natural derivative of hydroquinone, has been the subject of in vitro studies investigating its effects on the skin. Notably, a laboratory study examined the application of arbutin on human skin cells, revealing its ability to effectively inhibit melanin production, the pigment responsible for skin coloration.


Arbutin (CAS 497-76-7) References

  1. Simultaneous HPLC Determination of Arbutin, Niacinamide and 3-O-Ethyl Ascorbic Acid in Whitening Cream Products in the Presence of Parabens.  |  Permana, B., et al. 2023. J Chromatogr Sci. 61: 241-248. PMID: 35098294
  2. Arbutin improves gut development and serum lipids via Lactobacillus intestinalis.  |  Ma, J., et al. 2022. Front Nutr. 9: 948573. PMID: 36159503
  3. Arbutin Inhibited Heat Stress-Induced Apoptosis and Promoted Proliferation and Migration of Heat-Injured Dermal Fibroblasts and Keratinocytes by Activating PI3K/AKT Signaling Pathway.  |  Zhu, S., et al. 2022. Evid Based Complement Alternat Med. 2022: 8798861. PMID: 36159569
  4. Silencing FHL2 inhibits bleomycin-induced pulmonary fibrosis through the TGF-β1/Smad signaling pathway.  |  Shi, M., et al. 2023. Exp Cell Res. 423: 113470. PMID: 36641135
  5. Ethyl Gallate Isolated from Castanopsis cuspidata var. sieboldii Branches Inhibits Melanogenesis and Promotes Autophagy in B16F10 Cells.  |  Choi, MH., et al. 2023. Antioxidants (Basel). 12: PMID: 36829827
  6. Arbutin abrogates testicular ischemia/reperfusion injury in rats through repression of inflammation and ER stress.  |  Demir, EA., et al. 2023. Tissue Cell. 82: 102056. PMID: 36921493
  7. A robust electrochemical sensor based on N,S-FeNi3/C for simultaneous detection of hydroquinone and arbutin in cosmetics.  |  Li, Y., et al. 2023. Mikrochim Acta. 190: 150. PMID: 36952134
  8. Functional characterization of the phosphotransferase system in Parageobacillus thermoglucosidasius.  |  Bidart, GN., et al. 2023. Sci Rep. 13: 7131. PMID: 37130962
  9. Tetrahedral framework nucleic acid loaded with glabridin: A transdermal delivery system applicated to anti-hyperpigmentation.  |  He, J., et al. 2023. Cell Prolif. e13495. PMID: 37132449
  10. Synthesis, in silico modelling, and in vitro biological evaluation of substituted pyrazole derivatives as potential anti-skin cancer, anti-tyrosinase, and antioxidant agents.  |  Boateng, ST., et al. 2023. J Enzyme Inhib Med Chem. 38: 2205042. PMID: 37184042
  11. Bioavailability of Coix Seed Polyphenols in a MKN28/Caco-2 Continuous Transport Model and Their Lipid-Lowering Effects via Modulating Adipocyte Differentiation of 3T3-L1 Cells.  |  Qin, B., et al. 2023. J Agric Food Chem. 71: 8425-8436. PMID: 37233613
  12. Key secondary metabolite markers for Wuchang Daohuaxiang rice discrimination in China.  |  Zhao, L., et al. 2023. Food Res Int. 169: 112943. PMID: 37254367
  13. Fruit Characteristics of Transgenic pear (Pyrus communis L.) Trees During Long-Term Field Trials.  |  Lebedev, V. 2023. Plant Foods Hum Nutr.. PMID: 37354264

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Arbutin, 10 g

sc-221267
10 g
$120.00

Arbutin, 25 g

sc-221267A
25 g
$242.00