Date published: 2025-9-15

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Arachidonic Acid ethyl ester (CAS 1808-26-0)

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Alternate Names:
Ethyl Arachidonate
Application:
Arachidonic Acid ethyl ester is a fatty acid ethyl ester that increases cytosolic Ca2+ concentration
CAS Number:
1808-26-0
Molecular Weight:
332.53
Molecular Formula:
C22H36O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Arachidonic acid ethyl ester is a more lipophilic form of arachidonic acid and can be incorporated into dietary regimens or fed to cultured cells as a source of exogenous arachidonate. It is one of the fatty acid ethyl esters that increase cytosolic Ca2+ concentration leading to pancreatic acinar cell injury due to excessive consumption of ethanol. The ethyl esterified version does not retain the ability to inhibit dopamine uptake, unlike the non ethyl esterified version. Arachidonic acid is stored in tissue phospholipids in esterified form, where it comprises a small but critically controlled percentage of the polyunsaturated fatty acid pool.


Arachidonic Acid ethyl ester (CAS 1808-26-0) References

  1. Fatty acid composition and arachidonate metabolites in the livers of ethanol-treated rats fed an arachidonate-supplemented diet: effect of dietary fat.  |  Okita, M., et al. 1998. J Nutr Sci Vitaminol (Tokyo). 44: 745-56. PMID: 10197306
  2. Arachidonic acid stimulates a novel cocaine-sensitive cation conductance associated with the human dopamine transporter.  |  Ingram, SL. and Amara, SG. 2000. J Neurosci. 20: 550-7. PMID: 10632584
  3. Ethanol toxicity in pancreatic acinar cells: mediation by nonoxidative fatty acid metabolites.  |  Criddle, DN., et al. 2004. Proc Natl Acad Sci U S A. 101: 10738-43. PMID: 15247419
  4. Melittin stimulates fatty acid release through non-phospholipase-mediated mechanisms and interacts with the dopamine transporter and other membrane-spanning proteins.  |  Keith, DJ., et al. 2011. Eur J Pharmacol. 650: 501-10. PMID: 20969853
  5. Production of prostaglandins, isoprostanes and thromboxane by Aspergillus fumigatus: identification by gas chromatography-tandem mass spectrometry and quantification by enzyme immunoassay.  |  Kupfahl, C., et al. 2012. Mol Immunol. 49: 621-7. PMID: 22118804
  6. Ligand determinants of fatty acid activation of the pronociceptive ion channel TRPA1.  |  Redmond, WJ., et al. 2014. PeerJ. 2: e248. PMID: 24516781
  7. Pathophysiology and Biomarker Potential of Fatty Acid Ethyl Ester Elevation During Alcoholic Pancreatitis.  |  Vela, S., et al. 2021. Gastroenterology. 161: 1513-1525. PMID: 34303660
  8. Metabolomics reveal alterations in arachidonic acid metabolism in Schistosoma mekongi after exposure to praziquantel.  |  Chienwichai, P., et al. 2021. PLoS Negl Trop Dis. 15: e0009706. PMID: 34473691
  9. Serum Untargeted UHPLC-HRMS-Based Lipidomics to Discover the Potential Biomarker of Colorectal Advanced Adenoma.  |  Zhu, Y., et al. 2021. Cancer Manag Res. 13: 8865-8878. PMID: 34858060
  10. Transcriptomic and Metabolomic Profiling Reveals That KguR Broadly Impacts the Physiology of Uropathogenic Escherichia coli Under in vivo Relevant Conditions.  |  Yang, D., et al. 2021. Front Microbiol. 12: 793391. PMID: 34975816
  11. Propolis: An update on its chemistry and pharmacological applications.  |  Hossain, R., et al. 2022. Chin Med. 17: 100. PMID: 36028892
  12. Multivariate Analysis Revealed Ultrasonic-Assisted Extraction Improves Anti-Melanoma Activity of Non-Flavonoid Compounds in Indonesian Brown Algae Ethanol Extract.  |  Sunarwidhi, AL., et al. 2022. Molecules. 27: PMID: 36364336
  13. Deuterated Drugs and Biomarkers in the COVID-19 Pandemic.  |  Jansen-van Vuuren, RD., et al. 2022. ACS Omega. 7: 41840-41858. PMID: 36440130

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Arachidonic Acid ethyl ester, 25 mg

sc-205208
25 mg
$47.00

Arachidonic Acid ethyl ester, 100 mg

sc-205208A
100 mg
$118.00