AQ-RA 741 CAS: 123548-16-3
MF: C27H37N5O2
MW: 463.62
A high affinity selective mAChR M2 antagonist.

AQ-RA 741 (CAS 123548-16-3)

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Alternate Names: 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,11-[2-[4-[4-(diethylamino)butyl]-1-piperidinyl]acetyl]-5,11-dihydro-
Application: AQ-RA 741 is a high affinity selective mAChR M2 antagonist
CAS Number: 123548-16-3
Molecular Weight: 463.62
Molecular Formula: C27H37N5O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

AQ-RA 741 is a high affinity, selective mAChR M2 antagonist (pKi values are 8.3, 7.7, and 6.82 for mAChR M2, mAChR M1, and mAChR M3 receptors, respectively). AQ-RA 741 displays cardioselectivity over tracheal, intestinal and bladder muscarinic receptors. AQ-RA 741 also inhibits vagally and agonist-induced bradycardia.

Physical State :
Solid
Solubility :
Soluble in ethanol (100 mM), DMSO (100 mM), and 1 equivalent HCl (100 mM).
Storage :
Desiccate at room temperature
Melting Point :
285.44° C (Predicted)
Boiling Point :
~602.7° C at 760 (Predicted)
Density :
~1.1 g/cm3 (Predicted)
Refractive Index :
n20D 1.57 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
129989
MDL Number :
MFCD00884623
SMILES :
CCN(CC)CCCCC1CCN(CC1)CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4

Download SDS (MSDS)

Certificate of Analysis

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