AQ-RA 741 is a high affinity, selective mAChR M2 antagonist (pKi values are 8.3, 7.7, and 6.82 for mAChR M2, mAChR M1, and mAChR M3 receptors, respectively). AQ-RA 741 displays cardioselectivity over tracheal, intestinal and bladder muscarinic receptors. AQ-RA 741 also inhibits vagally and agonist-induced bradycardia.
Soluble in ethanol (100 mM), DMSO (100 mM), and 1 equivalent HCl (100 mM).
Desiccate at room temperature
285.44° C (Predicted)
~602.7° C at 760 (Predicted)
~1.1 g/cm3 (Predicted)
n20D 1.57 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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