Aposcopolamine (CAS 535-26-2)
See product citations (7)
QUICK LINKS
Apohyoscine, a naturally occurring alkaloid present in various plants of the Apocynaceae family, exhibits potent inhibitory properties against acetylcholinesterase (AChE). This enzyme is responsible for the degradation of acetylcholine, a neurotransmitter. Apohyoscine has been utilized for diverse purposes, including insecticidal and anesthetic applications. Apohyoscine has been extensively employed in scientific research, serving as an insecticide, an anesthetic, and useful for studying the effects of acetylcholine on the nervous system. By inhibiting the enzyme acetylcholinesterase, apohyoscine effectively prevents the breakdown of acetylcholine. Consequently, apohyoscine leads to increased levels of acetylcholine, thereby eliciting a range of effects on the nervous system.
Aposcopolamine (CAS 535-26-2) References
- Liquid chromatographic determination of hyoscine (scopolamine) in urine using solid phase extraction. | Whelpton, R., et al. 1992. Biomed Chromatogr. 6: 198-204. PMID: 1643390
- Metabolism in vivo of the tropane alkaloid, scopolamine, in several mammalian species. | Wada, S., et al. 1991. Xenobiotica. 21: 1289-300. PMID: 1796606
- Liquid chromatography-electrospray ionization ion trap mass spectrometry for analysis of in vivo and in vitro metabolites of scopolamine in rats. | Chen, H., et al. 2008. J Chromatogr Sci. 46: 74-80. PMID: 18218192
- Analysis of scopolamine and its eighteen metabolites in rat urine by liquid chromatography-tandem mass spectrometry. | Chen, H., et al. 2005. Talanta. 67: 984-91. PMID: 18970269
- Quantitative microtiter fibronectin fibrillogenesis assay: use in high throughput screening for identification of inhibitor compounds. | Tomasini-Johansson, BR., et al. 2012. Matrix Biol. 31: 360-7. PMID: 22986508
- Multi-analysis determination of tropane alkaloids in cereals and solanaceaes seeds by liquid chromatography coupled to single stage Exactive-Orbitrap. | Marín-Sáez, J., et al. 2017. J Chromatogr A. 1518: 46-58. PMID: 28870544
- Screening of drugs and homeopathic products from Atropa belladonna seed extracts: Tropane alkaloids determination and untargeted analysis. | Marín-Sáez, J., et al. 2018. Drug Test Anal. 10: 1579-1589. PMID: 29808589
- Integrated meta-analysis, network pharmacology, and molecular docking to investigate the efficacy and potential pharmacological mechanism of Kai-Xin-San on Alzheimer's disease. | Yi, P., et al. 2020. Pharm Biol. 58: 932-943. PMID: 32956608
- High-pressure liquid chromatographic determination of methscopolamine nitrate, phenylpropanolamine hydrochloride, pyrilamine maleate, and pheniramine maleate in tablets. | Heidemann, DR. 1981. J Pharm Sci. 70: 820-2. PMID: 7264941
- Sulphotransferase-dependent dehydration of atropine and scopolamine in guinea pig. | Wada, S., et al. 1994. Xenobiotica. 24: 853-61. PMID: 7810167
- Alkaloids of Datura ferox from Argentina. | Vitale, AA., et al. 1995. J Ethnopharmacol. 49: 81-9. PMID: 8847888
- Alkaloid variation within Duboisia myoporoides | Wandee Gritsanapan, William J. Griffin a. 1991. Phytochemistry. 30: 2667-2669.
- The Characteristics of Atropine Metabolism in Cultured Tissues and Seedlings of Duboisia | Y. Kitamura, R. Yamashita, C. Yabiku, H. Mura & M. Watanabe. 1995. Current Issues in Plant Molecular and Cellular Biology. 22: 653–658.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aposcopolamine, 10 mg | sc-210830 | 10 mg | $326.00 | |||
Aposcopolamine, 25 mg | sc-210830A | 25 mg | $775.00 | |||
Aposcopolamine, 50 mg | sc-210830B | 50 mg | $1408.00 | |||
Aposcopolamine, 100 mg | sc-210830C | 100 mg | $2280.00 |