apoOL Antibody (G-6): sc-390958
- apoOL Antibody (G-6) is a mouse monoclonal IgG2a κ apoOL antibody, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 239-262 near the C-terminus of apoOL of human origin
- apoOL Antibody (G-6) is recommended for detection of apoOL of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine and bovine
- Anti-apoOL Antibody (G-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for apoOL Antibody (G-6) for WB and IHC(P) applications. These reagents are now offered in bundles with apoOL Antibody (G-6) (see ordering information below).
apoOL Antibody (G-6) is a mouse monoclonal IgG2a kappa light chain antibody that detects apoOL protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-apoOL antibody (G-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. apoOL protein, also known as FAM121A, is a 268 amino acid secreted protein that plays a crucial role in lipid metabolism, particularly in cholesterol transport. apoOL is primarily found in high-density lipoproteins (HDLs) and low-density lipoproteins (LDLs), where secretion occurs through a microsomal triglyceride transfer protein-dependent mechanism. apoOL′s importance lies in potential involvement in regulating cholesterol levels and preventing lipid accumulation in the heart, which is vital for cardiovascular health. Additionally, apoOL is encoded by a gene located on human chromosome X, a region containing over 1,000 genes, highlighting this protein′s complexity and significance in various biological processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
apoOL Antibody (G-6) References:
- Lipoprotein secretion and triglyceride stores in the heart. | Bjorkegren, J., et al. 2001. J Biol Chem. 276: 38511-7. PMID: 11481337
- Apolipoprotein A-V: a novel apolipoprotein associated with an early phase of liver regeneration. | van der Vliet, HN., et al. 2001. J Biol Chem. 276: 44512-20. PMID: 11577099
- Nitroxides inhibit peroxyl radical-mediated DNA scission and enzyme inactivation. | Offer, T. and Samuni, A. 2002. Free Radic Biol Med. 32: 872-81. PMID: 11978488
- Lipoprotein production by the heart: a novel pathway of triglyceride export from cardiomyocytes. | Nielsen, LB. 2002. Scand J Clin Lab Invest Suppl. 237: 35-40. PMID: 12570165
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. | Clark, HF., et al. 2003. Genome Res. 13: 2265-70. PMID: 12975309
- ApoO, a novel apolipoprotein, is an original glycoprotein up-regulated by diabetes in human heart. | Lamant, M., et al. 2006. J Biol Chem. 281: 36289-302. PMID: 16956892
- Homocysteine enhances LDL fatty acid peroxidation, promoting microalbuminuria in type 2 diabetes. | Kassab, A., et al. 2008. Ann Clin Biochem. 45: 476-80. PMID: 18753419
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
apoOL Antibody (G-6) | sc-390958 | 200 µg/ml | $322.00 | |||
apoOL Antibody (G-6): m-IgG Fc BP-HRP Bundle | sc-530315 | 200 µg Ab; 10 µg BP | $361.00 | |||
apoOL Antibody (G-6): m-IgGκ BP-HRP Bundle | sc-523751 | 200 µg Ab, 40 µg BP | $361.00 | |||
apoOL Antibody (G-6) AC | sc-390958 AC | 500 µg/ml, 25% agarose | $424.00 | |||
apoOL Antibody (G-6) HRP | sc-390958 HRP | 200 µg/ml | $322.00 | |||
apoOL Antibody (G-6) FITC | sc-390958 FITC | 200 µg/ml | $336.00 | |||
apoOL Antibody (G-6) PE | sc-390958 PE | 200 µg/ml | $349.00 | |||
apoOL Antibody (G-6) Alexa Fluor® 488 | sc-390958 AF488 | 200 µg/ml | $364.00 | |||
apoOL Antibody (G-6) Alexa Fluor® 546 | sc-390958 AF546 | 200 µg/ml | $364.00 | |||
apoOL Antibody (G-6) Alexa Fluor® 594 | sc-390958 AF594 | 200 µg/ml | $364.00 | |||
apoOL Antibody (G-6) Alexa Fluor® 647 | sc-390958 AF647 | 200 µg/ml | $364.00 | |||
apoOL Antibody (G-6) Alexa Fluor® 680 | sc-390958 AF680 | 200 µg/ml | $364.00 | |||
apoOL Antibody (G-6) Alexa Fluor® 790 | sc-390958 AF790 | 200 µg/ml | $364.00 | |||
apoOL (G-6) Neutralizing Peptide | sc-390958 P | 100 µg/0.5 ml | $69.00 |