apoC-II Antibody (3E4): sc-293340

apoC-II Antibody (3E4) is a mouse monoclonal IgG2a kappa light chain antibody that detects apoC-II protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). anti-apoC-II antibody (3E4) is available as the non-conjugated format. apoC-II protein plays a crucial role in lipid metabolism as a necessary cofactor for the activation of lipoprotein lipase, an enzyme responsible for hydrolyzing triglycerides in plasma and facilitating fatty acid transfer to tissues. This function is vital for maintaining normal lipid levels in the bloodstream and preventing conditions such as hyperlipidemia, which can lead to cardiovascular diseases. apoC-II protein is encoded by the human apoC-II gene, located on chromosome 19q13.2 and consists of 79 amino acids. Expression is primarily in the liver, where activation occurs during the differentiation of monocytes into macrophages, highlighting importance in both lipid metabolism and immune response. Regulation of lipoprotein lipase activity by apoC-II is essential for proper clearance of triglyceride-rich lipoproteins from circulation, underscoring significance in metabolic health.

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apoC-II Antibody (3E4) References:

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