Apolipoprotein A I/APOA1 Antibody (464CT10.4.4): sc-517307
- Apolipoprotein A I/APOA1 Antibody (464CT10.4.4) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a synthetic peptide corresponding to amino acids 10-37 in the N-terminal region of apoA-I of human origin
- recommended for detection of apoA-I of mouse, rat and human origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Apolipoprotein A I/APOA1 Antibody (464CT10.4.4). This work is in progress.
apoA-I Antibody (464CT10.4.4) is a mouse monoclonal IgG1 antibody that detects apolipoprotein A-I (apoA-I) in mouse, rat, and human samples through western blotting (WB). apoA-I is a crucial component of high-density lipoprotein (HDL) in plasma, consisting of a single chain of 243 amino acids that plays a vital role in cholesterol metabolism by promoting the efflux of cholesterol from peripheral tissues to the liver for excretion. This process is essential for maintaining lipid homeostasis and preventing atherosclerosis, a condition characterized by the buildup of fats, cholesterol, and other substances in and on the artery walls. Additionally, apoA-I serves as a cofactor for lecithin cholesterol acyltransferase (LCAT), an enzyme that catalyzes the formation of cholesteryl esters, further facilitating the transport and metabolism of lipids. apoA-I′s ability to influence plasma lipid levels underscores its importance in cardiovascular health, making apoA-I a significant target for research in lipid disorders and related diseases. anti-apoA-I antibody (464CT10.4.4) is an invaluable tool for researchers investigating the roles of apolipoproteins in lipid metabolism and cardiovascular disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Apolipoprotein A I/APOA1 Antibody (464CT10.4.4) | sc-517307 | 100 µg/ml | $316.00 |