

apoA-I Antibody (4) is a mouse monoclonal IgG1 antibody that detects apolipoprotein A-I (apoA-I) in mouse and rat samples through applications such as western blotting (WB) and immunoprecipitation (IP). apoA-I is a crucial component of high-density lipoprotein (HDL) in plasma, playing a vital role in lipid metabolism by promoting the efflux of cholesterol from peripheral tissues to the liver for excretion. This process is essential for maintaining cholesterol homeostasis and preventing atherosclerosis, a condition characterized by the buildup of fats, cholesterol, and other substances in and on the artery walls. The structure of apoA-I, which consists of a single chain of 243 amino acids, allows apoA-I to interact effectively with lipids and other proteins, facilitating apoA-I′s function as a cofactor for lecithin cholesterol acyltransferase (LCAT). LCAT is responsible for the formation of most plasma cholesteryl esters, further underscoring apoA-I′s importance in lipid transport and metabolism. anti-apoA-I antibody (4) enables researchers to gain insights into apoA-I′s role in various physiological and pathological processes, enhancing our understanding of cardiovascular health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Apolipoprotein A I/APOA1 Antibody (4) | sc-135837 | 50 µg/500 µl | $316.00 |