


ApoA-I Antibody (2G4) is a mouse monoclonal IgG1 antibody that detects apoA-I in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-apoA-I antibody (2G4) is available in a non-conjugated form, specifically designed for researchers seeking to study apoA-I′s role in lipid metabolism. ApoA-I monoclonal antibody (2G4) recognizes a crucial component of high-density lipoprotein (HDL) in plasma, where apoA-I plays a vital role in promoting cholesterol efflux from peripheral tissues to the liver, facilitating excess cholesterol excretion. This process is essential for maintaining lipid homeostasis and preventing atherosclerosis, making apoA-I a significant target for cardiovascular research. ApoA-I is primarily synthesized in the liver and intestines, and proper functioning is critical for HDL particle formation, which are responsible for transporting cholesterol and other lipids in the bloodstream. Additionally, apoA-I serves as a cofactor for lecithin cholesterol acyltransferase (LCAT), an enzyme that catalyzes the conversion of free cholesterol into cholesteryl esters, further underscoring apoA-I′s importance in lipid metabolism and cardiovascular health.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Apolipoprotein A I/APOA1 Antibody (2G4) | sc-69755 | 100 µl | $316.00 |