apo-Transferrin (CAS 11096-37-0)
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Alternate Names:
ATF; Siderophilin; Serotransferrin; β-1-metal-binding globulin
Application:
apo-Transferrin is a non-heme iron transport protein
CAS Number:
11096-37-0
Molecular Weight:
76-81 kDa
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Apo-Transferrin (ATF) is sourced from FDA approved plasma and has been tested and found negative for antibodies to many common human blood viruses. Apo-Transferrin plays a physiological role in the transportation and distribution of iron amongst bodily organs. Apo-Transferrin is also an important component used for the cultivation of mammalian cells in-vitro because it acts as a transport factor for defined culture media. This property is for long-term mammalian cell growth in-vitro since Apo-Transferrin operates as a detoxificant in media by binding to contaminating metal ions. Some other common uses for Apo-Transferrin are affinity purification and receptor mediated transfection of DNA-like molecules into cells.
apo-Transferrin (CAS 11096-37-0) References
- Apo-transferrin is internalized and routed differently from Fe-transferrin by caco-2 cells: a confocal microscopy study of vesicular transport in intestinal cells. | Alvarez-Hernandez, X., et al. 2000. Blood. 95: 721-3. PMID: 10627487
- The effect of apo-transferrin on bacterial adhesion to biomaterials. | Ardehali, R., et al. 2002. Artif Organs. 26: 512-20. PMID: 12072107
- Transferrin induces interleukin-18 expression in chronic myeloid leukemia cell line, K-562. | Park, S., et al. 2009. Leuk Res. 33: 315-20. PMID: 18835036
- A simple method for large-scale purification of plasma-derived apo-transferrin. | Ascione, E., et al. 2010. Biotechnol Appl Biochem. 57: 87-95. PMID: 20923415
- Interaction of apo-transferrin with anticancer ruthenium complexes NAMI-A and its reduced form. | Mazuryk, O., et al. 2012. J Inorg Biochem. 116: 11-8. PMID: 23010324
- Effects of human serum and apo-Transferrin on Staphylococcus epidermidis RP62A biofilm formation. | She, P., et al. 2016. Microbiologyopen. 5: 957-966. PMID: 27185376
- Citrate and albumin facilitate transferrin iron loading in the presence of phosphate. | Matias, C., et al. 2017. J Inorg Biochem. 168: 107-113. PMID: 28110161
- Inhibitory effect of transferrin on serum zinc measurement. | Orino, K. 2017. Biometals. 30: 615-621. PMID: 28677078
- Measurement of interaction behavior of six biologically important noble metal ions with the iron(III) binding protein, apo-transferrin, using mobility-shift affinity electrophoresis. | Alhazmi, HA. 2018. Pharmazie. 73: 143-149. PMID: 29544561
- Ferric pyrophosphate citrate: interactions with transferrin. | Pratt, R., et al. 2018. Biometals. 31: 1081-1089. PMID: 30311019
- Adjunctive transferrin to reduce the emergence of antibiotic resistance in Gram-negative bacteria. | Luna, BM., et al. 2019. J Antimicrob Chemother. 74: 2631-2639. PMID: 31170282
- Combination therapy of apo-transferrin and thyroid hormones enhances remyelination. | Rosato-Siri, MV., et al. 2021. Glia. 69: 151-164. PMID: 32818301
- Low-pressure chromatographic separation and UV/Vis spectrophotometric characterization of the native and desialylated human apo-transferrin. | Friganović, T., et al. 2021. Heliyon. 7: e08030. PMID: 34611562
- Malachite Green, the hazardous materials that can bind to Apo-transferrin and change the iron transfer. | Farhadian, S., et al. 2022. Int J Biol Macromol. 194: 790-799. PMID: 34838577
- Differential binding of apo and holo human transferrin to meningococci and co-localisation of the transferrin-binding proteins (TbpA and TbpB). | Powell, NB., et al. 1998. J Med Microbiol. 47: 257-64. PMID: 9511831
Inhibitor of:
EG434726, EG434727, EG434729, ferritin, and OTTMUSG00000016694.Activator of:
E330017A01Rik, and transferrin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
apo-Transferrin, 100 mg | sc-391092 | 100 mg | $150.00 | |||
apo-Transferrin, 500 mg | sc-391092A | 500 mg | $469.00 | |||
apo-Transferrin, 1 g | sc-391092B | 1 g | $744.00 |