Molecular structure of APF, CAS Number: 359010-70-1
APF (CAS 359010-70-1)
Alternate Names:
Aminophenyl fluorescein
Application:
APF is a fluorescent reagent used to detect highly reactive oxygen species
CAS Number:
359010-70-1
Purity:
≥98%
Molecular Weight:
423.4
Molecular Formula:
C26H17NO5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
APF is a fluorescent reagent (lambdaExmax: 490nm lambda Emmax: 515nm) used in the detection of highly reactive oxygen species (hROS). Immediately reacts with hROS such as hydroxyl radical, peroxynitrite and hypochlorite, and the fluorescence intensity greatly increases. When using APF together with HPF, it also allows for specific detection of hypochlorite (-OCl) to elucidate reliable roles of -OCl in biological systems such as netrophils. Peroxynitrite can also be detected in distinction from nitric oxide and superoxide since APF does not react with nitric oxide, superoxide and hydrogen peroxide. APF is resistant to light-induced autooxidation and is stable in aqueous solutions.
APF (CAS 359010-70-1) References
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- Identification and application of Phyto-Fenton reactions. | Inagaki, Y., et al. 2016. Chemosphere. 144: 1443-50. PMID: 26495829
- An Ultrasensitive Fluorescence Assay for the Detection of Halides and Enzymatic Dehalogenation. | Aslan-Üzel, AS., et al. 2020. ChemCatChem. 12: 2032-2039. PMID: 32362951
- Fluorescent Nanogel Sensors for X-ray Dosimetry. | Jiang, L., et al. 2021. ACS Sens. 6: 1643-1648. PMID: 33761245
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
APF, 1 mg | sc-202468 | 1 mg | $678.00 |