Antibiotic TPU-0037-A CAS: 485815-59-6
MF: C46H72N4O10
MW: 841.0
A structural analogue of lydicamycin shown to be active against MRSA.

Antibiotic TPU-0037-A (CAS 485815-59-6)

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Application: Antibiotic TPU-0037-A is a structural analogue of lydicamycin shown to be active against MRSA
CAS Number: 485815-59-6
Purity: >95%
Molecular Weight: 841.0
Molecular Formula: C46H72N4O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

TPU-0037A, a close structural analogue of lydicamycin, has been shown to be highly active against MRSA. TPU-0037A is also closely related to Antibiotic BN 4515N isolated from a strain of Microtetraspora as a neuritogenic agent.


References

1. TPU-0037-A, B, C and D, novel lydicamycin congeners with anti-MRSA activity from Streptomyces platensis TP-A0598. Furumai T. et al. J. Antibiot. 2002, 55, 873. 2. A new neuritogenetic compound BU-4514N produced by Microtetraspora sp.. Toda S. et al. J. Antibiot. 1993, 46, 875. 3. Lydicamycin, a new antibiotic of a novel skeletal type. II. Physico-chemical properties and structure elucidation. Hayakawa Y. et al. J. Antibiot. 1991, 44, 288. 4. Lydicamycin, a new antibiotic of a novel skeletal type. I. Taxonomy, fermentation, isolation and biological activity. Hayakawa Y. et al. J. Antibiot. 1991, 44, 282.

Appearance :
Film
Physical State :
Solid
Derived From :
Streptomyces sp.
Solubility :
Soluble in ethanol, methanol, DMSO, and DMF.
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
54729887
SMILES :
CC1=CC2C(CCC(C2CC1CCC(C)C(C(=CCC(C=CC(C)C(C=CCC(C=CCC(CC3CCCN3C(=N)N)O)O)O)O)C)O)(C)C(=C4C(=O)CNC4=O)O)O

Download SDS (MSDS)

Certificate of Analysis

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