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Anthraflavic acid (CAS 84-60-6)

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Alternate Names:
2,6-Dihydroxyanthraquinone; Anthraflavine
Application:
Anthraflavic acid is an anthraquinone
CAS Number:
84-60-6
Purity:
>92%
Molecular Weight:
240.21
Molecular Formula:
C14H8O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Anthraflavic acid is a naturally occurring quinone compound that can be found in numerous plants. It serves as a vital intermediate in the biosynthesis of various secondary metabolites, including anthraquinones, tannins, and other biopolymers. The precise mechanism of action of Anthraflavic acid remains partially understood. However, it is postulated that the compound has the capability to interact with different cellular components, such as proteins, lipids, and DNA, thereby modulating their activity.


Anthraflavic acid (CAS 84-60-6) References

  1. Differential modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1)-catalyzed estradiol-3-glucuronidation by the addition of UGT1A1 substrates and other compounds to human liver microsomes.  |  Williams, JA., et al. 2002. Drug Metab Dispos. 30: 1266-73. PMID: 12386134
  2. Biosynthesis of drug glucuronides for use as authentic standards.  |  Soars, MG., et al. 2002. J Pharmacol Toxicol Methods. 47: 161-8. PMID: 12628307
  3. The effect of incubation conditions on the enzyme kinetics of udp-glucuronosyltransferases.  |  Soars, MG., et al. 2003. Drug Metab Dispos. 31: 762-7. PMID: 12756209
  4. Structure-activity relationships of anthraquinones on the suppression of DNA-binding activity of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.  |  Fukuda, I., et al. 2009. J Biosci Bioeng. 107: 296-300. PMID: 19269596
  5. Microbial Synthesis of Non-Natural Anthraquinone Glucosides Displaying Superior Antiproliferative Properties.  |  Nguyen, TTH., et al. 2018. Molecules. 23: PMID: 30154376
  6. Induction of rat hepatic cytochrome P-450 I proteins by the antimutagen anthraflavic acid.  |  Ayrton, AD., et al. 1988. Food Chem Toxicol. 26: 909-15. PMID: 3209131
  7. Anthraflavic acid inhibits the mutagenicity of the food mutagen IQ: mechanism of action.  |  Ayrton, AD., et al. 1988. Mutat Res. 207: 121-5. PMID: 3282161
  8. Inhibition of epidermal xenobiotic metabolism in SENCAR mice by naturally occurring plant phenols.  |  Das, M., et al. 1987. Cancer Res. 47: 760-6. PMID: 3492267
  9. Anthraflavic acid is a potent and specific inhibitor of cytochrome P-448 activity.  |  Ayrton, AD., et al. 1987. Biochim Biophys Acta. 916: 328-31. PMID: 3689794
  10. Inhibition of polycyclic aromatic hydrocarbon-DNA adduct formation in epidermis and lungs of SENCAR mice by naturally occurring plant phenols.  |  Das, M., et al. 1987. Cancer Res. 47: 767-73. PMID: 3802081
  11. Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by tannic acid, hydroxylated anthraquinones and hydroxylated cinnamic acid derivatives.  |  Huang, MT., et al. 1985. Carcinogenesis. 6: 237-42. PMID: 3918802
  12. Inhibitors of cAMP-dependent protein kinase impair long-term memory formation in day-old chicks.  |  Zhao, WQ., et al. 1995. Neurobiol Learn Mem. 64: 106-18. PMID: 7582818
  13. Structure-activity relationships of anthraquinones as inhibitors of 7-ethoxycoumarin O-deethylase and mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline.  |  Hao, NJ., et al. 1995. Mutat Res. 328: 183-91. PMID: 7739602
  14. Extrapolation of in vitro antimutagenicity to the in vivo situation: the case for anthraflavic acid.  |  Ioannides, C., et al. 1993. Basic Life Sci. 61: 103-10. PMID: 8304922

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Anthraflavic acid, 1 g

sc-233880
1 g
$33.00

Anthraflavic acid, 5 g

sc-233880A
5 g
$153.00

Anthraflavic acid, 10 g

sc-233880B
10 g
$235.00

Anthraflavic acid, 50 g

sc-233880C
50 g
$816.00

Anthraflavic acid, 100 g

sc-233880D
100 g
$1428.00

Anthraflavic acid, 1 kg

sc-233880E
1 kg
$6528.00