Annexin III Antibody (21): sc-101511

Annexin III Antibody (21) is a mouse monoclonal IgG2b light chain antibody that detects Annexin III in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Annexin III, also known as ANXA3, Lipocortin III, and PAP-III, is a member of the annexin family of calcium-binding proteins, which bind phospholipids in a calcium-dependent manner. Anti-Annexin III antibody (21) recognizes a protein that plays a crucial role in various cellular processes, including ion flux regulation, endocytosis, and exocytosis, making Annexin III essential for maintaining cellular homeostasis and signaling. Notably, Annexin III inhibits phospholipase A2, an enzyme that can trigger arachidonic acid release and subsequent inflammatory responses, highlighting Annexin III′s importance in modulating inflammatory processes. Additionally, Annexin III′s structure, which includes four annexin repeats, enables specific interactions with phospholipids and proteins, emphasizing Annexin III′s role in cellular adhesion and membrane dynamics. With diverse functions and critical involvement in cellular regulation, anti-Annexin III antibody (21) serves as an invaluable tool for researchers studying cell biology and disease mechanisms.

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Annexin III Antibody (21) References:

1. miR-18b attenuates cerebral ischemia/reperfusion injury through regulation of ANXA3 and PI3K/Akt signaling pathway.  |  Min, XL., et al. 2020. Brain Res Bull. 161: 55-64. PMID: 32380186
2. ANXA3 is upregulated by hypoxia-inducible factor 1-alpha and promotes colon cancer growth.  |  Du, K., et al. 2020. Transl Cancer Res. 9: 7440-7449. PMID: 35117344
3. Upregulated of ANXA3, SORL1, and Neutrophils May Be Key Factors in the Progressionof Ankylosing Spondylitis.  |  Jiang, J., et al. 2022. Front Immunol. 13: 861459. PMID: 35464477
4. Mechanical force-promoted osteoclastic differentiation via periodontal ligament stem cell exosomal protein ANXA3.  |  Huang, HM., et al. 2022. Stem Cell Reports. 17: 1842-1858. PMID: 35868309
5. Discovery of a first-in-class ANXA3 degrader for the treatment of triple-negative breast cancer.  |  Liang, Y., et al. 2023. Acta Pharm Sin B. 13: 1686-1698. PMID: 37139408
6. ANXA3, associated with YAP1 regulation, participates in the proliferation and chemoresistance of cervical cancer cells.  |  Huang, J., et al. 2023. Genes Genomics. 45: 1575-1586. PMID: 37843781
7. Identification of ANXA3 as a biomarker associated with pyroptosis in ischemic stroke.  |  Liu, L., et al. 2023. Eur J Med Res. 28: 596. PMID: 38102696
8. ANXA3-Rich Exosomes Derived from Tumor-Associated Macrophages Regulate Ferroptosis and Lymphatic Metastasis of Laryngeal Squamous Cell Carcinoma.  |  Xu, L., et al. 2024. Cancer Immunol Res. 12: 614-630. PMID: 38393971
9. Proximity labeling of host factor ANXA3 in HCV infection reveals a novel LARP1 function in viral entry.  |  Bley, H., et al. 2024. J Biol Chem. 300: 107286. PMID: 38636657
10. Epstein-Barr virus causes vascular abnormalities in epithelial malignancies through upregulating ANXA3-HIF-1α-VEGF pathway.  |  Chen, Y., et al. 2024. Oncogene. 43: 2143-2159. PMID: 38778160

The preferred Annexin III antibody is Annexin III Antibody (E-11): sc-390502.