Annexin-2/ANXA2 (h): 293 Lysate: sc-111344

Annexin II (h): 293 Lysate is derived from the 293 cell line, a human embryonic kidney cell line widely used in molecular and cellular biology research due to its high transfection efficiency and reliable growth characteristics. This lysate is specifically enriched with human Annexin II, a calcium-dependent phospholipid-binding protein involved in various cellular processes, including membrane trafficking, cell signaling, and cytoskeletal organization. Annexin II functions by binding to phospholipid membranes in the presence of calcium ions, playing a key role in membrane fusion, exocytosis, and endocytosis. In research, Annexin II (h): 293 Lysate is utilized to study the biochemical and cellular functions of Annexin II. Researchers use this lysate in Western blotting to detect and quantify Annexin II expression levels, providing insights into its regulation and post-translational modifications under different experimental conditions. The lysate is also employed in co-immunoprecipitation assays to identify protein-protein interactions involving Annexin II, which helps explain its role in cellular signaling pathways and cytoskeletal dynamics. Additionally, this lysate is valuable in studies investigating the role of Annexin II in membrane-related processes such as vesicle trafficking and membrane repair. Researchers explore how Annexin II interacts with other proteins and lipids to mediate these essential cellular functions. The use of Annexin II (h): 293 Lysate allows for detailed examination of its mechanisms of action and its involvement in maintaining cellular homeostasis. The origin and quality of the 293 cell line are rigorously controlled, ensuring consistent and reproducible results in experimental research focused on fundamental biological processes.