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Annexin I Antibody (ANEX 5E4/1): sc-53158

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Datasheets
  • Annexin I Antibody (ANEX 5E4/1) is a mouse monoclonal IgG1, cited in 3 publications, provided at 200 µg/ml
  • raised against mixture of native membrane proteins from human bone tissues, including whole native annexin proteins
  • recommended for detection of Annexin I of human origin by WB, IP and IF
  • See Annexin I (EH17a): sc-12740 for Annexin I antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Annexin I Antibody (ANEX 5E4/1). This work is in progress.

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Annexin I Antibody (ANEX 5E4/1) is a mouse monoclonal IgG1 antibody designed to detect Annexin I, also known by its alternative names ANXA1 and Lipocortin I. Anti-Annexin I antibody (ANEX 5E4/1) is raised against a mixture of native membrane proteins from human bone tissues, including whole native annexin proteins, ensuring robust recognition of Annexin I in various assays. Annexin I is predominantly located in the cytoplasm of cells but can translocate to the cell membrane in response to inflammatory stimuli, a feature that is crucial for its role in mediating cellular responses. Functionally, Annexin I plays a significant role in anti-inflammatory processes by inhibiting phospholipase A2 (cPLA2), thereby reducing the production of pro-inflammatory eicosanoids. Additionally, Annexin I is involved in important cellular trafficking mechanisms such as endocytosis, exocytosis, and cellular adhesion, highlighting its importance in maintaining cellular homeostasis and responding to external signals. Precise detection of Annexin I is essential for researchers studying inflammation, cancer, and various other disease pathways where Annexin I is a key regulatory molecule. Anti-Annexin I antibody (ANEX 5E4/1) demonstrates strong reactivity with human Annexin I in applications including western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF), making this reagent a versatile tool for diverse experimental setups. Anti-Annexin I antibody (ANEX 5E4/1) supports advanced investigations into molecular mechanisms governing cellular responses and inflammatory processes.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Annexin I Antibody (ANEX 5E4/1)

sc-53158
200 µg/ml
$316.00

What is the recommended storage condition for Annexin I (ANEX 5E4/1): sc-53158?

Asked by: Professor Griffin
Thank you for your question. We recommend storing the antibody at 4° C.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by from Good specificity in WB in human AnnexinGood specificity in WB in human Annexin I transfected 293T whole cell lysate. -SCBT QC
Date published: 2015-01-29
Rated 5 out of 5 by from Strong band seen in WB in SKStrong band seen in WB in SK-N-SH, K-562, U-937 and PC-3 whole cell lysates. -SCBT QC
Date published: 2013-06-18
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Annexin I Antibody (ANEX 5E4/1) is rated 5.0 out of 5 by 2.
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