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Annexin I Antibody (ANEX 5E4/1) is a mouse monoclonal IgG1 antibody designed to detect Annexin I, also known by its alternative names ANXA1 and Lipocortin I. Anti-Annexin I antibody (ANEX 5E4/1) is raised against a mixture of native membrane proteins from human bone tissues, including whole native annexin proteins, ensuring robust recognition of Annexin I in various assays. Annexin I is predominantly located in the cytoplasm of cells but can translocate to the cell membrane in response to inflammatory stimuli, a feature that is crucial for its role in mediating cellular responses. Functionally, Annexin I plays a significant role in anti-inflammatory processes by inhibiting phospholipase A2 (cPLA2), thereby reducing the production of pro-inflammatory eicosanoids. Additionally, Annexin I is involved in important cellular trafficking mechanisms such as endocytosis, exocytosis, and cellular adhesion, highlighting its importance in maintaining cellular homeostasis and responding to external signals. Precise detection of Annexin I is essential for researchers studying inflammation, cancer, and various other disease pathways where Annexin I is a key regulatory molecule. Anti-Annexin I antibody (ANEX 5E4/1) demonstrates strong reactivity with human Annexin I in applications including western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF), making this reagent a versatile tool for diverse experimental setups. Anti-Annexin I antibody (ANEX 5E4/1) supports advanced investigations into molecular mechanisms governing cellular responses and inflammatory processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Annexin I Antibody (ANEX 5E4/1) | sc-53158 | 200 µg/ml | $316.00 |