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Aniline hydrochloride (CAS 142-04-1)

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Alternate Names:
Benzenamine HCl
Application:
Aniline hydrochloride is The acute toxicity involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin.
CAS Number:
142-04-1
Purity:
≥99%
Molecular Weight:
129.59
Molecular Formula:
C6H5NH2•HCl
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Aniline hydrochloride is a colorless solid with excellent solubility in water. In scientific research, aniline hydrochloride serves as a versatile reagent for synthesizing various compounds and a catalyst for chemical reactions. It also acts as an additive in certain solvents, enhancing their functionality. Aniline hydrochloride exhibits proton acceptor properties, allowing it to accept protons from molecules, leading to the formation of new compounds in a process known as a proton transfer reaction. The reversible nature of this reaction enables the proton to be returned to the original molecule, making aniline hydrochloride a valuable asset in various chemical reactions.


Aniline hydrochloride (CAS 142-04-1) References

  1. Lack of clastogenic activity of aniline hydrochloride in the mouse bone marrow.  |  Jones, E. and Fox, V. 2003. Mutagenesis. 18: 283-5. PMID: 12714695
  2. High-dose clastogenic activity of aniline in the rat bone marrow and its relationship to the carcinogenicity in the spleen of rats.  |  Bomhard, EM. 2003. Arch Toxicol. 77: 291-7. PMID: 12734644
  3. Bioassay of aniline hydrochloride for possible carcinogenicity.  |  ,. 1978. Natl Cancer Inst Carcinog Tech Rep Ser. 130: 1-115. PMID: 12799662
  4. Biomonitoring of aromatic amines VI: determination of hemoglobin adducts after feeding aniline hydrochloride in the diet of rats for 4 weeks.  |  Zwirner-Baier, I., et al. 2003. Arch Toxicol. 77: 672-7. PMID: 14557919
  5. Protective effects of dioscorea alata L. In aniline exposure-induced spleen toxicity in rats: a biochemical study.  |  Khan, R., et al. 2014. Toxicol Int. 21: 294-9. PMID: 25948969
  6. Ameliorative Effect of Chronic Supplementation of Protocatechuic Acid Alone and in Combination with Ascorbic Acid in Aniline Hydrochloride Induced Spleen Toxicity in Rats.  |  Khairnar, U., et al. 2016. Scientifica (Cairo). 2016: 4306984. PMID: 27418998
  7. Exploring the Critical Factors Limiting Polyaniline Biocompatibility.  |  Kašpárková, V., et al. 2019. Polymers (Basel). 11: PMID: 30960346
  8. Polymerization of aniline hydrochloride in reverse of microemulsion by batch and semicontinuous process using ionic and nonionic surfactants.  |  Pier Villegas, G., et al. 2022. Des Monomers Polym. 25: 89-97. PMID: 35431615
  9. Halogen Bond-Driven Aggregation-Induced Emission Skeleton: N-(3-(Phenylamino)allylidene) Aniline Hydrochloride.  |  Chang, Y., et al. 2023. ACS Appl Mater Interfaces.. PMID: 36763789
  10. Teratologic and postnatal evaluation of aniline hydrochloride in the Fischer 344 rat.  |  Price, CJ., et al. 1985. Toxicol Appl Pharmacol. 77: 465-78. PMID: 3975914
  11. Splenic fibrosis and sarcomas in F344 rats fed diets containing aniline hydrochloride, p-chloroaniline, azobenzene, o-toluidine hydrochloride, 4,4'-sulfonyldianiline, or D & C red No. 9.  |  Goodman, DG., et al. 1984. J Natl Cancer Inst. 73: 265-73. PMID: 6588231
  12. Aniline and aniline hydrochloride.  |  . 1982. IARC Monogr Eval Carcinog Risk Chem Hum. 27: 39-61. PMID: 6955268
  13. Acute hematopoietic toxicity of aniline in rats.  |  Khan, MF., et al. 1997. Toxicol Lett. 92: 31-7. PMID: 9242355

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Aniline hydrochloride, 5 g

sc-252377
5 g
$40.00