Anastrozole-d12 (CAS 120512-32-5)
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Anastrozole-d12 is a deuterated variant of anastrozole, a compound that selectively inhibits the aromatase enzyme, pivotal in the biosynthesis of estrogens from androgen precursors. This alteration, where twelve hydrogen atoms are replaced with deuterium, aims to enhance the molecule′s metabolic stability, making it particularly valuable in pharmacokinetic and metabolic studies. By hindering the aromatase enzyme′s activity, anastrozole-d12 serves as a tool in biochemical and molecular biology research to understand the role of estrogens in various biological processes. Its application in research applications provides insights into the mechanisms underlying the regulation of estrogen levels and their impact on cellular and molecular pathways. This enhanced understanding is for elucidating the complex interplay between hormones and their biological effects, contributing significantly to the field of endocrinology and the study of hormone-related disorders.
Anastrozole-d12 (CAS 120512-32-5) References
- Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2. | Dudenkov, TM., et al. 2019. Clin Pharmacol Ther. 106: 219-227. PMID: 30648747
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Anastrozole-d12, 1 mg | sc-217649 | 1 mg | $278.00 |