Ampicillin sodium salt, cell culture grade (CAS 69-52-3)
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Ampicillin sodium salt, cell culture grade is a beta-lactam antibiotic within the penicillin family. As a member of this family, it is susceptible to beta-lactamase, which hydrolyzes the beta-lactam ring. This broad spectrum antibiotic is effective against gram-positive, gram-negative, and anaerobic bacteria. Ampicillin sodium salt, cell culture grade is widely used in cell culture as a selective agent. As an antibiotic, it binds to penicillin binding proteins (PBPs) on a susceptible organism and inhibits cell wall synthesis by interfering with the enzymes responsible for the formation of the organism′s cell wall. After binding to the PBPs, Ampicillin sodium salt, cell culture grade acts as a structural analogue of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme, and thereby prevents the cross-linking of the peptidoglycan of the cell wall necessary for the growth of the bacterium. Potency: ≥ 845 µg Ampicillin/mg (anhydrous)
Ampicillin sodium salt, cell culture grade (CAS 69-52-3) References
- A new method for protein coexpression in Escherichia coli using two incompatible plasmids. | Yang, W., et al. 2001. Protein Expr Purif. 22: 472-8. PMID: 11483011
- Unstable Escherichia coli L forms revisited: growth requires peptidoglycan synthesis. | Joseleau-Petit, D., et al. 2007. J Bacteriol. 189: 6512-20. PMID: 17586646
- Ampicillin/sulbactam: current status in severe bacterial infections. | Rafailidis, PI., et al. 2007. Drugs. 67: 1829-49. PMID: 17722953
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ampicillin sodium salt, cell culture grade, 5 g | sc-202951 | 5 g | $65.00 | |||
Ampicillin sodium salt, cell culture grade, 100 g | sc-202951A | 100 g | $410.00 | |||
Ampicillin sodium salt, cell culture grade, 1 kg | sc-202951B | 1 kg | $2075.00 |