Date published: 2026-5-20

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Amphotericin B Methyl Ester (CAS 36148-89-7)

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CAS Number:
36148-89-7
Molecular Weight:
938.106
Molecular Formula:
C48H75NO17
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Amphotericin B methyl ester (ABME) as a lipophilic substance, Amphotericin B Methyl Ester is utilized in laboratory research to investigate the biochemical and physiological characteristics of amphotericin B. The compound is applied in particularly concerning the study of pathogenic fungi and in the exploration of new antifungal compounds. In research applications, Amphotericin B methyl ester is known for its ability to attach to fungal cell walls and disrupt cell membranes. This interaction leads to the leakage of cellular contents and ultimately causes the destruction of the fungal cells.


Amphotericin B Methyl Ester (CAS 36148-89-7) References

  1. Stimulatory effect of amphotericin B methyl ester on the grwoth of L-M and Vero cells.  |  Fisher, PB., et al. 1975. J Antibiot (Tokyo). 28: 896-902. PMID: 1201972
  2. Comparison of amphotericin B and amphotericin B methyl ester: efficacy in murine coccidioidomycosis and toxicity.  |  Lawrence, RM. and Hoeprich, PD. 1976. J Infect Dis. 133: 168-74. PMID: 1245764
  3. Synthesis and biophysical studies on 35-deoxy amphotericin B methyl ester.  |  Szpilman, AM., et al. 2009. Chemistry. 15: 7117-28. PMID: 19544513
  4. Antiviral effects of amphotericin B methyl ester.  |  Jordan, GW. and Seet, EC. 1978. Antimicrob Agents Chemother. 13: 199-204. PMID: 206201
  5. Effect of amphotericin B methyl ester on vesicular stomatitis virus morphology.  |  Jordan, GW., et al. 1978. Antimicrob Agents Chemother. 13: 340-1. PMID: 206202
  6. Stability studies with amphotericin B and amphotericin B methyl ester.  |  Bonner, DP., et al. 1975. J Antibiot (Tokyo). 28: 132-5. PMID: 234414
  7. The Perpendicular Orientation of Amphotericin B Methyl Ester in Hydrated Lipid Bilayers Supports the Barrel-Stave Model.  |  Yamamoto, T., et al. 2019. Biochemistry. 58: 2282-2291. PMID: 30973009
  8. Design, synthesis and biological evaluation of a novel N-aminoacyl derivative of amphotericin B methyl ester as an antifungal agent.  |  Zhang, J., et al. 2021. Eur J Med Chem. 211: 113104. PMID: 33360798
  9. Comparative pharmacology of amphotericin B and amphotericin B methyl ester in the non-human primate, Macacca mulatta.  |  Jagdis, FA., et al. 1977. Antimicrob Agents Chemother. 12: 582-90. PMID: 411419
  10. Amphotericin B methyl ester hydrochloride and amphotericin B: comparative acute toxicity.  |  Keim, GR., et al. 1973. Science. 179: 584-5. PMID: 4686465
  11. Equilibrium binding of amphotericin B and its methyl ester and borate complex to sterols.  |  Readio, JD. and Bittman, R. 1982. Biochim Biophys Acta. 685: 219-24. PMID: 7059605
  12. Amphotericin B methyl ester and leukoencephalopathy: the other side of the coin.  |  Hoeprich, P. 1982. J Infect Dis. 146: 173-6. PMID: 7108269
  13. Comparative toxicological studies of amphotericin B methyl ester and amphotericin B in mice, rats, and dogs.  |  Keim, GR., et al. 1976. Antimicrob Agents Chemother. 10: 687-90. PMID: 984803

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Amphotericin B Methyl Ester, 50 mg

sc-353010
50 mg
$1025.00