Molecular structure of Amorolfine hydrochloride, CAS Number: 78613-38-4
Amorolfine hydrochloride (CAS 78613-38-4)
Alternate Names:
Loceryl; Amorolfin; Curanail
Application:
Amorolfine hydrochloride is a broad-based antifungal agent which blocks ergosterol biosynthesis
CAS Number:
78613-38-4
Purity:
≥99%
Molecular Weight:
353.97
Molecular Formula:
C21H35ON•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Amorolfine hydrochloride is extensively used in the field of biochemistry for studying fungal cell membrane integrity and function. Its role in inhibiting the synthesis of sterols in fungal cells provides a basis for exploring cellular mechanisms that govern membrane structure and resilience. Researchers employ Amorolfine hydrochloride to examine the biochemical pathways involved in sterol production, which are for maintaining cell membrane stability and functionality in fungi. This research is fundamental in understanding how fungal organisms adapt and survive under various environmental stressors. Moreover, the study of Amorolfine hydrochloride′s action helps in elucidating the molecular interactions within the cell membranes, offering insights into broader applications in biochemistry and cell biology.
Amorolfine hydrochloride (CAS 78613-38-4) References
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- Simultaneous determination of triacetin, acetic ether, butyl acetate and amorolfine hydrochloride in amorolfine liniment by HPLC. | Gao, Y., et al. 2012. Pak J Pharm Sci. 25: 389-94. PMID: 22459467
- Comparison of in vitro antifungal activities of efinaconazole and currently available antifungal agents against a variety of pathogenic fungi associated with onychomycosis. | Jo Siu, WJ., et al. 2013. Antimicrob Agents Chemother. 57: 1610-6. PMID: 23318803
- Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes. | Hau, CS., et al. 2013. J Dermatol Sci. 71: 174-83. PMID: 23688403
- Potential of Chemical and Physical Enhancers for Transungual Delivery of Amorolfine Hydrochloride. | Šveikauskaitė, I., et al. 2019. Materials (Basel). 12: PMID: 30925734
- In vitro anti-Pythium insidiosum activity of amorolfine hydrochloride and azithromycin, alone and in combination. | Ianiski, LB., et al. 2021. Med Mycol. 59: 67-73. PMID: 32400872
- In vitro antifungal susceptibility patterns of Trichophyton benhamiae complex isolates from diverse origin. | Shamsizadeh, F., et al. 2021. Mycoses. 64: 1378-1386. PMID: 33864711
- Fungal Melanonychia as a Solitary Black Linear Vertical Nail Plate Streak: Case Report and Literature Review of Candida-Associated Longitudinal Melanonychia Striata. | Cohen, PR. and Shurman, J. 2021. Cureus. 13: e14248. PMID: 33959438
- Identification and functional validation of FDA-approved positive and negative modulators of the mitochondrial calcium uniporter. | De Mario, A., et al. 2021. Cell Rep. 35: 109275. PMID: 34161774
- In vitro activities of 8 antifungal agents against geophilic dermatophyte isolates. | Shamsizadeh, F., et al. 2022. Mycoses. 65: 255-262. PMID: 34861084
- Synthesis, Biological Evaluation, and Structure-Activity Relationships of 4-Aminopiperidines as Novel Antifungal Agents Targeting Ergosterol Biosynthesis. | Krauß, J., et al. 2021. Molecules. 26: PMID: 34885791
- Updated Perspectives on the Diagnosis and Management of Onychomycosis. | Falotico, JM. and Lipner, SR. 2022. Clin Cosmet Investig Dermatol. 15: 1933-1957. PMID: 36133401
- The potential role and mechanism of circRNA/miRNA axis in cholesterol synthesis. | Chen, W., et al. 2023. Int J Biol Sci. 19: 2879-2896. PMID: 37324939
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Nop14.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Amorolfine hydrochloride, 100 mg | sc-357290 | 100 mg | $64.00 | |||
Amorolfine hydrochloride, 1 g | sc-357290A | 1 g | $530.00 |