Molecular structure of Ammonium tetrathiomolybdate, CAS Number: 15060-55-6
Ammonium tetrathiomolybdate (CAS 15060-55-6)
Alternate Names:
Ammonium tetrathiomolybdate also known as Ammonium molybdenum sulfide; Ammonium thiomolybdate; Diammonium tetrathiomolybdate
Application:
Ammonium tetrathiomolybdate is classic building block for transition metal sulfide cluster compounds
CAS Number:
15060-55-6
Molecular Weight:
260.28
Molecular Formula:
(NH4)2MoS4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ammonium tetrathiomolybdate is a classic building block for transition metal sulfide cluster compounds was recently used in a low-temperature, solid state synthesis of a new series of heterometallic sulfide clusters stabilized with dppm [bis(diphenylphosphino)methane] ligands. Ammonium tetrathiomolybdate leads to the ring opening of aziridines leading to sulfides and disulfides. Ammonium tetrathiomolybdate also acts as a chelator in vivo to reduce copper levels.
Ammonium tetrathiomolybdate (CAS 15060-55-6) References
- Ammonium tetrathiomolybdate delays onset, prolongs survival, and slows progression of disease in a mouse model for amyotrophic lateral sclerosis. | Tokuda, E., et al. 2008. Exp Neurol. 213: 122-8. PMID: 18617166
- Ammonium tetrathiomolybdate as a water-soluble and slow-release hydrogen sulfide donor. | Xu, S., et al. 2016. Bioorg Med Chem Lett. 26: 1585-1588. PMID: 26898812
- Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin. | Chisholm, CL., et al. 2016. Oncotarget. 7: 84439-84452. PMID: 27806319
- Ammonium tetrathiomolybdate following ischemia/reperfusion injury: Chemistry, pharmacology, and impact of a new class of sulfide donor in preclinical injury models. | Dyson, A., et al. 2017. PLoS Med. 14: e1002310. PMID: 28678794
- Ammonium tetrathiomolybdate enhances the antitumor effects of cetuximab via the suppression of osteoclastogenesis in head and neck squamous carcinoma. | Morisawa, A., et al. 2018. Int J Oncol. 52: 989-999. PMID: 29328370
- Advances in Treatment of Wilson Disease. | Aggarwal, A. and Bhatt, M. 2018. Tremor Other Hyperkinet Mov (N Y). 8: 525. PMID: 29520330
- Ammonium tetrathiomolybdate treatment of copper-associated hepatopathy in dogs. | Langlois, DK., et al. 2019. J Vet Intern Med. 33: 1336-1343. PMID: 30883912
- Ammonium tetrathiomolybdate enhances the antitumor effect of cisplatin via the suppression of ATPase copper transporting beta in head and neck squamous cell carcinoma. | Ryumon, S., et al. 2019. Oncol Rep. 42: 2611-2621. PMID: 31638244
- Is Hydrogen Sulfide a Concern During Treatment of Lung Adenocarcinoma With Ammonium Tetrathiomolybdate? | Li, X., et al. 2020. Front Oncol. 10: 234. PMID: 32195181
- Ammonium tetrathiomolybdate in the decoppering phase treatment of Wilson's disease with neurological symptoms: A case series. | De Fabregues, O., et al. 2020. Brain Behav. 10: e01596. PMID: 32202078
- Neuroprotective effects of ammonium tetrathiomolybdate, a slow-release sulfide donor, in a rodent model of regional stroke. | Mendonça, BP., et al. 2020. Intensive Care Med Exp. 8: 13. PMID: 32274608
- Ammonium tetrathiomolybdate triggers autophagy-dependent NRF2 activation in vascular endothelial cells. | Zhang, M., et al. 2022. Cell Death Dis. 13: 733. PMID: 36008391
- A Molybdenum Polysulfide In-Situ Generated from Ammonium Tetrathiomolybdate for High-Capacity and High-Power Rechargeable Magnesium Battery Cathodes. | Chen, D., et al. 2022. ACS Nano. 16: 20510-20520. PMID: 36410730
Inhibitor of:
ADAMTS-13, ATP7B, COA6, COL6A3, COPT2, CUTC, GNS, HAH1, Heme Oxygenase 1, Laminin γ-3, melanopsin, Metallothionein, MOXD2, NUBP2, SFXN5, and STEAP.Activator of:
catalase, COMMD10, COMMD7, COMMD9, CTR1, Cup1, Metallothionein 4, OTTMUSG00000017374, and SCO1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ammonium tetrathiomolybdate, 1 g | sc-239242 | 1 g | $46.00 | |||
Ammonium tetrathiomolybdate, 10 g | sc-239242A | 10 g | $199.00 | |||
Ammonium tetrathiomolybdate, 25 g | sc-239242B | 25 g | $413.00 | |||
Ammonium tetrathiomolybdate, 50 g | sc-239242C | 50 g | $515.00 |